The US National Weather Service said it expects Southwest US to face persistent dangerous heat through Saturday, with daytime highs expected between 110 and 115 degree Fahrenheit.
Similar weather conditions are expected to develop again in the southern Plains again starting from the weekend.
Meanwhile, the Carolinas is likely to experience heavy to excessive rain on Friday, with potential for isolated areas of flash flooding.
The NWS issued an extreme heat warning for Arizona's Kingman, Lake Havasu City, Bullhead City, Yuma, Parker, Gila Bend, Dateland, Ajo, Wickenburg, Phoenix, Casa Grande, Globe, Prescott, Tucson, Nogales, Grand Canyon Village, Sierra Vista, Safford, Willcox, Benson, Bisbee, San Carlos, Oracle, Oro Valley, and Green Valley.
Arizona is primarily served by Pinnacle West Capital (PNW) unit Arizona Public Service Company, and UNS Energy subsidiaries Unisource and Tucson Electric Power.
An extreme heat warning was raised for Las Vegas and Beatty in Nevada, which falls under the service area of Berkshire Hathaway Energy unit NV Energy, were also placed under a similar warning.
In California, an extreme heat warning was issued for Palm Springs, Blythe, El Centro Imperial, Twentynine Palms, Barstow, Baker, Death Valley, Victorville, Burbank, Los Angeles, Santa Monica, Beaumont, Riverside, Ontario, Chino, Palm Springs, Indio, Hemet, Temecula, Anaheim, Santa Ana, San Clemente, Borrego Springs, Escondido, Julian, Mount Laguna, El Cajon, Campo, Palmdale, Santa Clarita, Long Beach, Avalon, Malibu, Oxnard, Santa Barbara, Lompoc, and Santa Maria.
Meanwhile, a red flag warning was raised for San Luis Obispo, Paso Robles, King City, Salinas, Monterey, Hollister, Santa Cruz, San Jose, and parts of Santa Maria.
PG&E (PCG) subsidiary Pacific Gas and Electric, Edison International's (EIX) Southern California Edison, and Sempra Energy (SRE) unit San Diego Gas & Electric are the major electricity service providers in these places.
The NWS also issued flash flood warnings for Alamogordo in New Mexico, served by TXNM (TXNM) subsidiary Public Service Company of New Mexico; and Snowshoe in West Virginia, where FirstEnergy (FE) unit Mon Power is the major service provider.
Pennsylvania's Harrisburg and Lancaster, which primarily fall under the service area of PPL (PPL) subsidiary PPL Electric Utilities, were covered under a flood warning.
Flood warnings were also raised for Canton, Havana, and areas near Carmi in Illinois; and Indiana's Vincennes, and nearby areas bordering Illinois.