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Wire

Smith+Nephew's TESSA Spatial Surgery System Gets US FDA De Novo Classification

Smith+Nephew (SNN) said Wednesday it has obtained De Novo classification by the US Food and Drug Administration for its TESSA spatial surgery system.The system uses computing and AI technology to support personalized planning, augmented reality, advanced imaging and other features to back arthroscopic procedures, the company said.The system's first indication for use is femoral anterior cruciate ligament reconstruction surgery of the knee, according to the company.The system will be launched in Q3 2026 and will see wider deployment next year, the company said.Price: $32.54, Change: $-0.03, Percent Change: -0.08%

$SNN
Asia Markets

European Equities Traded in the US as American Depositary Receipts Rise in Friday Trading

European equities traded in the US as American depositary receipts were tracking higher late Friday morning, rising 0.55% to 1,910.34 on the S&P Europe Select ADR Index, which is up about 0.4% for the week so far.From continental Europe, the gainers were led by software firm SAP (SAP) and semiconductor company Sequans Communications (SQNS), which rose 7% and 2.8%, respectively. They were followed by pharmaceutical firm Novo Nordisk (NVO) and lender Banco Santander (SAN), which advanced 2.5% and 2.4%, respectively.The decliners from continental Europe were led by telecommunications company Nokia (NOK) and biopharmaceutical company DBV Technologies (DBVT), which dropped 4.7% and 2.9% respectively. They were followed by internet ad firm Criteo (CRTO) and biotech company BioNTech (BNTX), which lost 2.1% and 1.3% respectively.The gainers from the UK were led by biopharmaceutical company Biodexa Pharmaceuticals (BDRX) and communications company WPP (WPP), which increased 3.7% and 2.3% respectively. They were followed by medical device maker Smith & Nephew (SNN) and educational publisher Pearson (PSO), which were up 1.7% and 1.6% respectively.The decliners from the UK and Ireland were led by pharmaceutical company Silence Therapeutics (SLN) and biopharmaceutical company Bicycle Therapeutics (BCYC), which fell 4.7% and 3% respectively. They were followed by biopharmaceutical company Akari Therapeutics (AKTX) and biotech firm Autolus Therapeutics (AUTL), which were down 2.5% and 2% respectively.

$AKTX$AUTL$BCYC$BNTX$CRTO$DBVT$NOK$NVO$PSO$SAN$SAP$SLN$SNN$SQNS$WPP
Asia Markets

European Equities Traded in the US as American Depositary Receipts Rise in Tuesday Trading

European equities traded in the US as American depositary receipts were heading higher late Tuesday morning, rising 0.7% to 1,919.96 on the S&P Europe Select ADR Index.From continental Europe, the gainers were led by 3D printer company Materialise (MTLS) and biopharmaceutical company Cellectis (CLLS), which rose 3.4% and 2% respectively. They were followed by telecommunications company Nokia (NOK) and petroleum refiner Equinor (EQNR), which were up 1.5% and 1% respectively.The decliners from continental Europe were led by furniture maker Natuzzi (NTZ) and consumer goods company Unilever (UL), which dropped 2.1% and 1.5% respectively. They were followed by pharmaceutical company Sanofi (SNY) and semiconductor company Sequans Communications (SQNS), which lost 1.3% each.The gainers from the UK were led by biopharmaceutical company Bicycle Therapeutics (BCYC) and lender Lloyds Banking Group (LYG), which advanced 3% and 2.2% respectively. They were followed by software firm Endava (DAVA) and educational publisher Pearson (PSO), which increased 2% and 1.4% respectively.The decliners from the UK and Ireland were led by biotech firm Trinity Biotech (TRIB) and medical device maker Smith & Nephew (SNN), which fell 5.4% each, and 3.5% respectively. They were followed by telecommunications operator Vodafone Group (VOD) and biopharmaceutical company Biodexa Pharmaceuticals (BDRX), which were down 3.8% and 3.5% respectively.

$BCYC$BDRX$CLLS$DAVA$EQNR$LYG$MTLS$NOK$NTZ$PSO$SNN$SNY$SQNS$TRIB$UL$VOD
Asia Markets

European Equities Traded in the US as American Depositary Receipts Decline in Wednesday Trading

European equities traded in the US as American depositary receipts were lower late Wednesday morning, falling 0.83% to 1,868.68 on the S&P Europe Select ADR Index.From continental Europe, the gainers were led by 3D printer company Materialise (MTLS) and medical device maker EDAP TMS (FOCL), which rose 5.5% and 4.8% respectively. They were followed by semiconductor company Sequans Communications (SQNS) and consumer goods company Unilever (UL), which were up 1.7% and 1.3% respectively.The decliners from continental Europe were led by biopharmaceutical firm Cellectis (CLLS) and petroleum refiner Equinor (EQNR), which dropped 5.4% and 3.5% respectively. They were followed by oil and gas company Eni (E) and telecommunications company Ericsson (ERIC), which were down 3.1% and 1.8% respectively.The gainers from the UK were led by Silence Therapeutics (SLN) and Trinity Biotech (TRIB), which surged 15% and 9.3% respectively. They were followed by Biodexa Pharmaceuticals (BDRX) and medical device maker Smith & Nephew (SNN), which advanced 4.1% and 2.4% respectively.The decliners from the UK and Ireland were led by Akari Therapeutics (AKTX) and Autolus Therapeutics (AUTL), which fell 8.7% and 3.5% respectively. They were followed by oil and gas company BP (BP) and Mereo BioPharma Group (MREO), which lost 3.1% and 2.9% respectively.

$AKTX$AUTL$BDRX$BP$CLLS$E$EQNR$ERIC$FOCL$MREO$MTLS$SLN$SNN$SQNS$TRIB$UL
Asia Markets

European Equities Traded in the US as American Depositary Receipts Rise in Monday Trading

European equities traded in the US as American depositary receipts started the week higher late Monday morning, advancing 0.61% to 1,903.57 on the S&P Europe Select ADR Index.From continental Europe, the gainers were led by pharmaceutical company Novo Nordisk (NVO) and telecommunications company Nokia (NOK), which rose 4.5% and 4.2% respectively. They were followed by internet browser company Opera (OPRA) and biopharmaceutical company DBV Technologies (DBVT), which were up 2.8% and 1.8% respectively.The decliners from continental Europe were led by biopharmaceutical company Cellectis (CLLS) and pharmaceutical company Sanofi (SNY), which fell 5% and 2.8% respectively. They were followed by internet advertising firm Criteo (CRTO) and semiconductor company Sequans Communications (SQNS), which were down 2.6% and 2.4% respectively.The gainers from the UK were led by pharmaceutical company Silence Therapeutics (SLN) and biopharmaceutical company Amarin (AMRN), which advanced 5.7% and 4.6% respectively. They were followed by lenders Lloyds Banking Group (LYG) and Barclays (BCS), which increased 4% and 3.8% respectively.The decliners from the UK and Ireland were led by biopharmaceutical company NuCana (NCNA) and mining company BHP Group (BHP), which lost 3.1% and 2% respectively. They were followed by telecommunications operator Vodafone Group (VOD) and medical device maker Smith & Nephew (SNN), which dropped 1.8% and 0.8% respectively.

$AMRN$BCS$BHP$CLLS$CRTO$DBVT$LYG$NCNA$NOK$NVO$OPRA$SLN$SNN$SNY$SQNS$VOD
Asia Markets

European Equities Traded in the US as American Depositary Receipts Increase in Friday Trading; Rise for Week

European equities traded in the US as American depositary receipts were trending higher late Friday morning, rising 0.53% to 1,917.29 on the S&P Europe Select ADR Index, which is up more than 2% for the week so far.From continental Europe, the gainers were led by biotech firm Evaxion (EVAX) and telecommunications company Nokia (NOK), which advanced 8.2% and 5.8% respectively. They were followed by biopharmaceutical company DBV Technologies (DBVT) and pharmaceutical company Ascendis Pharma (ASND), which increased 4.8% and 3.2% respectively.The decliners from continental Europe were led by accommodations booking company trivago (TRVG) and medical device maker EDAP TMS (FOCL), which dropped 3.2% and 1.5% respectively. They were followed by software firm SAP (SAP) and semiconductor company Sequans Communications (SQNS), which lost 1.3% and 0.6% respectively.The gainers from the UK were led by biopharmaceutical company Mereo BioPharma Group (MREO) and software firm Endava (DAVA), which rose 3.7% and 3.4% respectively. They were followed by pharmaceutical company Silence Therapeutics (SLN) and biotech firm Autolus Therapeutics (AUTL), which were up 2.7% and 1.9% respectively.The decliners from the UK and Ireland were led by biotech firm Trinity Biotech (TRIB) and biopharmaceutical company Akari Therapeutics (AKTX), which fell 3.7% and 3.4% respectively. They were followed by medical device maker Smith & Nephew (SNN) and pharmaceutical company AstraZeneca (AZN), which were off 0.9% and 0.6% respectively.

$AKTX$ASND$AUTL$AZN$DAVA$DBVT$EVAX$FOCL$MREO$NOK$SAP$SLN$SNN$SQNS$TRIB$TRVG
Asia Markets

European Equities Traded in the US as American Depositary Receipts Track Lower in Wednesday Trading

European equities traded in the US as American depositary receipts were declining late Wednesday morning, falling 0.58% to 1,880.17 on the S&P Europe Select ADR Index.From continental Europe, the gainers were led by telecommunications company Nokia (NOK) and petroleum refiner Equinor (EQNR), which rose 2.1% and 1.3%, respectively. They were followed by oil and gas company Eni (E) and biopharmaceutical company argenx (ARGX), which were up 1% and 0.5%, respectively.The decliners from continental Europe were led by internet ad firm Criteo (CRTO) and biopharmaceutical company Cellectis (CLLS), which fell 7% and 4.7%, respectively. They were followed by biotech firm Evaxion (EVAX) and software company SAP (SAP), which were down 4.6% and 4.5%, respectively.The gainers from the UK were led by Mereo BioPharma Group (MREO), which advanced 5.6%. It was followed by pharmaceutical company Silence Therapeutics (SLN) and medical device maker Smith & Nephew (SNN), which increased 4.8% and 2%, respectively.The decliners from the UK and Ireland were led by communications company WPP (WPP) and software company Endava (DAVA), which dropped 4.5% and 4.4%, respectively. They were followed by lender Barclays (BCS) and biotech firm Autolus Therapeutics (AUTL), which lost 2.4% and 1.7%, respectively.

$ARGX$AUTL$BCS$CLLS$CRTO$DAVA$E$EQNR$EVAX$MREO$NCNA$NOK$SAP$SLN$SNN$WPP
Asia Markets

European Equities Traded in the US as American Depositary Receipts Trend Lower in Tuesday Trading

European equities traded in the US as American depositary receipts were trending lower late Tuesday morning, declining 0.3% to 1,824.16 on the S&P Europe Select ADR Index.From continental Europe, the gainers were led by software firm SAP (SAP) and internet advertising company Criteo (CRTO), which advanced 5.3% and 3.6% respectively. They were followed by biopharmaceutical company argenx (ARGX) and petroleum refiner Equinor (EQNR), which rose 2.1% and 1.3% respectively.The decliners from continental Europe were led by semiconductor company Sequans Communications (SQNS) and telecommunications company Nokia (NOK), which dropped 3.5% and 2.7% respectively. They were followed by biopharmaceutical company Cellectis (CLLS) and medical device maker EDAP TMS (EDAP), which were off 2.6% and 1.6% respectively.The gainers from the UK were led by biopharmaceutical companies Akari Therapeutics (AKTX) and NuCana (NCNA), which were up 4.9% and 3.5% respectively. They were followed bybiopharmaceutical company Biodexa Pharmaceuticals (BDRX) and medical device company Smith & Nephew (SNN), which were up 3.1% and 2.6% respectively.The decliners from the UK and Ireland were led by biotech firm Autolus Therapeutics (AUTL), which fell 8%, followed by mining company BHP Group (BHP) and pharmaceutical company Silence Therapeutics (SLN), which lost 3% and 0.6% respectively.

$AKTX$ARGX$AUTL$BDRX$BHP$CLLS$CRTO$EDAP$EQNR$NCNA$NOK$SAP$SLN$SNN$SQNS
Asia Markets

European Equities Traded in the US as American Depositary Receipts Rise Friday

European equities traded in the US as American depositary receipts were higher late Friday morning, rising 0.78% to 1,826.25 on the S&P Europe Select ADR Index, which is up 1.3% for the week so far.From continental Europe, the gainers were led by telecommunications company Nokia (NOK) and biotech firm Evaxion (EVAX), which rose 4.7% and 4.4% respectively. They were followed by oil and gas company Eni (E) and lender Banco Bilbao Vizcaya Argentaria (BBVA), which increased 2.6% and 2.5% respectively.The decliners from continental Europe were led by software firm SAP (SAP) and semiconductor firm Sequans Communications (SQNS), which fell 1.6% and 1.2% respectively. They were followed by biopharmaceutical company DBV Technologies (DBVT) and internet browser company Opera (OPRA), which were off 1% and 0.9% respectively.The gainers from the UK were led by Lloyds Banking Group (LYG), which rose 3%. It was followed by telecommunications operator Vodafone Group (VOD) and InterContinental Hotels Group (IHG), which were up 2.7% and 2.6% respectively.The decliners from the UK and Ireland were led by Biodexa Pharmaceuticals (BDRX) and educational publisher Pearson (PSO), which lost 4.9% and 1.5% respectively. They were followed by medical device maker Smith & Nephew (SNN) and software company Endava (DAVA), which fell 1.3% and 1.2% respectively.

$BBVA$BDRX$DAVA$DBVT$E$EVAX$IHG$LYG$NOK$OPRA$PSO$SAP$SNN$SQNS$VOD
Research

Research Alert: CFRA Keeps Hold Opinion On Adss Of Smith & Nephew

CFRA, an independent research provider, has providedwith the following research alert. Analysts at CFRA have summarized their opinion as follows:We lower our target price to USD33 from USD37, implying a 2026 P/E of 14.8x. This is broadly in line with its three-year historical forward P/E of 15x. While we see positives from its stronger positioning following the completion of the 12-Point Plan and additional upside from the RISE strategy, our optimism is tempered by rising execution risk in the U.S. Knee Implant business. Our EPS estimates remain unchanged. Smith & Nephew's (SN) Q1 2026 underlying revenue growth of 3.1% decelerated sequentially across all segments, particularly Orthopaedics due to U.S. Knee Implants weakness. SN reiterated its 2026 guidance of 6% underlying revenue growth and USD1.3B trading profit. We expect upcoming launches and continued execution of the RISE strategy to support growth momentum, but execution on U.S. Knee Implants remains critical to monitor. The cementless LANDMARK launch is an important catalyst to address persistent challenges in the knee business, in our view.

$SNN
Research

Research Alert: Smith & Nephew Q1: Strong Sports Medicine Offsets Knee Implants Weakness

CFRA, an independent research provider, has providedwith the following research alert. Analysts at CFRA have summarized their opinion as follows:Smith & Nephew (SN) posted Q1 2026 revenue of USD1,501M, in line with consensus, representing underlying growth of 3.1% (or 4.4% on an adjusted daily sales basis) but decelerating sequentially across all segments. Orthopaedics slowed to +0.8% (vs. Q4's +7.9%) due to U.S. Knee Implants weakness, while Sports Medicine & ENT remained solid at +6.7%. SN announced a new USD500M share buyback to be completed within the next 12 months and reaffirmed 2026 guidance of 6% underlying revenue growth and USD1.3B trading profit. The 2026 guidance for reported revenue guidance of 7.7% is above the current S&P Capital IQ consensus estimate of around 6.6%. We expect upcoming launches and continued execution of the new RISE strategy to underpin growth momentum. That said, execution on U.S. Knee Implants remains critical to monitor. In our view, the planned Q3 2026 launch of the cementless version of the LANDMARK Knee System represents an important catalyst to address persistent challenges in the Knee business.

$SNN
Asia Markets

European Equities Traded in the US as American Depositary Receipts Track Lower in Monday Trading

European equities traded in the US as American depositary receipts were trending lower late Monday morning, down 0.39% to 1,794.56 on the S&P Europe Select ADR Index.From continental Europe, the gainers were led by telecommunications company Nokia (NOK) and semiconductor company Sequans Communications (SQNS), which climbed 6.8% and 5.6% respectively. They were followed by 3D printer company Materialise (MTLS) and biopharmaceutical company DBV Technologies (DBVT), which advanced 3.5% and 3.4% respectively.The decliners from continental Europe were led by biotech firm BioNTech (BNTX) and internet browser company Opera (OPRA), which dropped 2.9% and 1.5% respectively. They were followed by oil and gas company Eni (E) and accommodations booking site trivago (TRVG), which lost 1% and 0.7% respectively.The gainers from the UK were led by medical device maker Smith & Nephew (SNN), which rose 1.4%. They were followed by biopharmaceutical company NuCana (NCNA) and biotech firm Autolus Therapeutics (AUTL), which were up 1.3% and 1% respectively.The decliners from the UK and Ireland were led by biopharmaceutical company Akari Therapeutics (AKTX) and cruise line operator Carnival (CUK), which fell 6% and 1.6% respectively. They were followed by oil and gas company Shell (SHEL) and hospitality company InterContinental Hotels Group (IHG), which were down 1.4% and 1.2% respectively.

$AKTX$AUTL$BNTX$CUK$DBVT$E$IHG$MTLS$NCNA$NOK$OPRA$SHEL$SNN$SQNS$TRVG
Wire

Smith & Nephew Says CARTIHEAL Implant Shows Compelling 5-Year Outcomes

Smith & Nephew (SNN) said Tuesday that new data from a clinical trial show "compelling" long-term results for its CARTIHEAL AGILI-C cartilage repair implant.The company said the study found the implant outperformed standard surgical care across all measured time points up to five years, adding that the patients treated with the implant reported better pain relief and improved quality of life over the five-year period. They also showed greater improvements in daily activities, sports, and recreation at two, four, and five years after treatment, according to a statement.The study also found similar outcomes in patients with and without osteoarthritis, the company added.The implant recently received a category one current procedural terminology code for procedures that will take effect on Jan. 1, 2027, the company said.Shares of Smith & Nephew were down nearly 3.4% in the session.Price: $33.04, Change: $-1.17, Percent Change: -3.42%

$SNN
Asia Markets

European Equities Traded in the US as American Depositary Receipts Rise in Friday Trading

European equities traded in the US as American depositary receipts were tracking higher late Friday morning, gaining 0.75% to 1,828.19 on the S&P Europe Select ADR Index, which is up 4% for the week.From continental Europe, the gainers were led by biopharmaceutical company Cellectis (CLLS) and lender Banco Bilbao Vizcaya Argentaria (BBVA), which climbed 6.6% and 2% respectively. They were followed by health-tech conglomerate Royal Philips (PHG) and biopharmaceutical company Grifols (GRFS), which rose 1.6% and 1.4% respectively.The decliners from continental Europe were led by biopharmaceutical company DBV Technologies (DBVT) and internet browser company Opera (OPRA), which fell 2.7% and 2.5% respectively. They were followed by internet advertising firm Criteo (CRTO) and pharmaceutical company Ascendis Pharma (ASND), which dropped 1.8% and 1.4% respectively.The gainers from the UK were led by biotech firm Autolus Therapeutics (AUTL) and biopharmaceutical company Biodexa Pharmaceuticals (BDRX), which advanced 5.1% and 4.3% respectively. They were followed by biotech company Trinity Biotech (TRIB) and medical device maker Smith & Nephew (SNN), which were up 2.3% and 2.1% respectively.The decliners from the UK and Ireland were led by pharmaceutical company Silence Therapeutics (SLN) and software firm Endava (DAVA), which lost 4.6% and 2.1% respectively. They were followed by biopharmaceutical companies Akari Therapeutics (AKTX) and Amarin (AMRN), which were down 1.9% and 1.5% respectively.

$AKTX$AMRN$ASND$AUTL$BBVA$BDRX$CLLS$CRTO$DAVA$DBVT$GRFS$OPRA$PHG$SLN$SNN$TRIB

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