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Ascendis Pharma's Yorvipath Has Superior Profile Relative to Competitors, Wedbush Says

Ascendis Pharma's (ASND) Yorvipath hypoparathyroidism therapy maintains a superior clinical profile compared with competing programs, Wedbush analysts said in a Monday note.The company's 3.5-year data from the phase-3 PaTHway study and the 5-year data from the phase-2 PaTH Forward study of Yorvipath in hypoparathyroidism provide strong evidence for sustained clinical benefit from long-term treatment, analysts said.Wedbush said that both studies showed high retention rates, durable efficacy, and continued improvement in renal function with longer treatment.Quality of life improvement, which is now required by the FDA for approvals, is the strongest evidence for Yorvipath's efficacy, a key opinion leader said, according to analysts.Wedbush has an outperform rating and a $273 price target on the stock.Price: $223.74, Change: $+5.68, Percent Change: +2.60%

$ASND
Asia Markets

European Equities Traded in the US as American Depositary Receipts Increase in Friday Trading; Rise for Week

European equities traded in the US as American depositary receipts were trending higher late Friday morning, rising 0.53% to 1,917.29 on the S&P Europe Select ADR Index, which is up more than 2% for the week so far.From continental Europe, the gainers were led by biotech firm Evaxion (EVAX) and telecommunications company Nokia (NOK), which advanced 8.2% and 5.8% respectively. They were followed by biopharmaceutical company DBV Technologies (DBVT) and pharmaceutical company Ascendis Pharma (ASND), which increased 4.8% and 3.2% respectively.The decliners from continental Europe were led by accommodations booking company trivago (TRVG) and medical device maker EDAP TMS (FOCL), which dropped 3.2% and 1.5% respectively. They were followed by software firm SAP (SAP) and semiconductor company Sequans Communications (SQNS), which lost 1.3% and 0.6% respectively.The gainers from the UK were led by biopharmaceutical company Mereo BioPharma Group (MREO) and software firm Endava (DAVA), which rose 3.7% and 3.4% respectively. They were followed by pharmaceutical company Silence Therapeutics (SLN) and biotech firm Autolus Therapeutics (AUTL), which were up 2.7% and 1.9% respectively.The decliners from the UK and Ireland were led by biotech firm Trinity Biotech (TRIB) and biopharmaceutical company Akari Therapeutics (AKTX), which fell 3.7% and 3.4% respectively. They were followed by medical device maker Smith & Nephew (SNN) and pharmaceutical company AstraZeneca (AZN), which were off 0.9% and 0.6% respectively.

$AKTX$ASND$AUTL$AZN$DAVA$DBVT$EVAX$FOCL$MREO$NOK$SAP$SLN$SNN$SQNS$TRIB$TRVG
Asia Markets

European Equities Traded in the US as American Depositary Receipts Rise in Friday Trading; Flat for Week

European equities traded in the US as American depositary receipts were rising late Friday morning, up 0.61% to 1,880.61 on the S&P Europe Select ADR Index, which is nearly flat for the week so far.From continental Europe, the gainers were led by medical device maker EDAP TMS (EDAP) and biotech firm BioNTech (BNTX), which rose 4.3% and 3% respectively. They were followed by software company SAP (SAP) and internet advertising firm Criteo (CRTO), which were up 2% and 0.4% respectively.The decliners from continental Europe were led by pharmaceutical company Ascendis Pharma (ASND) and telecommunications company Nokia (NOK), which fell 7.3% and 3% respectively. They were followed by accommodations booking site trivago (TRVG) and biopharmaceutical company Cellectis (CLLS), which were off 0.9% and 0.8% respectively.The gainers from the UK were led by biopharmaceutical company Biodexa Pharmaceuticals (BDRX) and communications company WPP (WPP), which advanced 2.4% and 1.1% respectively. They were followed by lenders Barclays (BCS) and HSBC (HSBC), which increased 1% and 0.9% respectively.The decliners from the UK and Ireland were led by biopharmaceutical companies Mereo BioPharma Group (MREO) and NuCana (NCNA), which dropped 6.6% and 4.4% respectively. They were followed by pharmaceutical company Silence Therapeutics (SLN) and tobacco company British American Tobacco (BTI), which lost 3.5% and 1.8% respectively.

$ASND$BCS$BDRX$BNTX$BTI$CLLS$CRTO$EDAP$HSBC$MREO$NCNA$NOK$SAP$SLN$TRVG$WPP
Asia Markets

European Equities Traded in the US as American Depositary Receipts Track Higher in Tuesday Trading

European equities traded in the US as American depositary receipts were trending higher late Tuesday morning, rising 0.73% to 1,891.94 on the S&P Europe Select ADR Index.From continental Europe, the gainers were led by accommodations booking site trivago (TRVG) and telecommunications company Nokia (NOK), which rose 6.4% and 4.8% respectively. They were followed by lenders Banco Bilbao Vizcaya Argentaria (BBVA) and Banco Santander (SAN), which were up 4.4% and 3.8% respectively.The decliners from continental Europe were led by pharmaceutical company Ascendis Pharma (ASND) and petroleum refiner Equinor (EQNR), which fell 3% and 2% respectively. They were followed by internet advertising firm Criteo (CRTO) and pharmaceutical company Novo Nordisk (NVO), which were down 1.1% and 0.2% respectively.The gainers from the UK were led by biopharmaceutical company Mereo BioPharma Group (MREO) and pharmaceutical company Silence Therapeutics (SLN), which climbed 16% and 6.3% respectively. They were followed by biotech firm Trinity Biotech (TRIB) and biopharmaceutical company Biodexa Pharmaceuticals (BDRX), which advanced 4.5% and 3.1% respectively.The decliners from the UK and Ireland were led by oil and gas company BP (BP) and biopharmaceutical company NuCana (NCNA), which dropped 5% and 2.4% respectively. They were followed by biopharmaceutical company Amarin (AMRN) and communications company WPP (WPP), which lost 1.6% and 1.5% respectively.

$AMRN$ASND$BBVA$BDRX$BP$CRTO$EQNR$MREO$NCNA$NOK$NVO$SAN$SLN$TRIB$TRVG$WPP
Asia Markets

European Equities Traded in the US as American Depositary Receipts Open Week Tracking Higher in Monday Trading

European equities traded in the US as American depositary receipts were heading higher late Monday morning, rising 0.88% to 1,825.10 on the S&P Europe Select ADR Index.From continental Europe, the gainers were led by biotech firm Evaxion (EVAX) and healthcare tech company Royal Philips (PHG), which rose 4.6% and 2.9% respectively. They were followed by internet advertising firm Criteo (CRTO) and biopharmaceutical company Grifols (GRFS), which were up 2.8% each.The decliners from continental Europe were led by biopharmaceutical company DBV Technologies (DBVT) and biotech firm BioNTech (BNTX), which dropped 3.2% and 2% respectively. They were followed by telecommunications company Nokia (NOK) and pharmaceutical company Ascendis Pharma (ASND), which were down 1.9% and 0.9% respectively.The gainers from the UK were led by biotech companies Autolus Therapeutics (AUTL) and Trinity Biotech (TRIB), which climbed 16% and 6.2% respectively. They were followed by communications company WPP (WPP) and educational publisher Pearson (PSO), which advanced 4.8% and 4.7% respectively.The decliners from the UK and Ireland were led by biopharmaceutical companies NuCana (NCNA) and Biodexa Pharmaceuticals (BDRX), which fell 8.3% and 3% respectively. They were followed by biopharmaceutical companies Amarin (AMRN) and Mereo BioPharma Group (MREO), which were off 2.1% and 1% respectively.

$AMRN$ASND$AUTL$BDRX$BNTX$CRTO$DBVT$EVAX$GRFS$MREO$NCNA$NOK$PHG$PSO$TRIB$WPP
Asia Markets

European Equities Traded in the US as American Depositary Receipts Flat in Wednesday Trading

European equities traded in the US as American depositary receipts were little changed late Wednesday morning, edging 0.08% higher to 1,829.64 on the S&P Europe Select ADR Index.From continental Europe, the gainers were led by telecommunications company Nokia (NOK) and biotech firm Evaxion (EVAX), which rose 4.1% and 3.9% respectively. They were followed by pharmaceutical company Ascendis Pharma (ASND) and accommodations booking site trivago (TRVG), which were up 0.5% and 0.3% respectively.The decliners from continental Europe were led by software firm SAP (SAP) and medical device maker EDAP TMS (EDAP), which dropped 4.8% and 4.7% respectively. They were followed by biopharmaceutical company DBV Technologies (DBVT) and furniture maker Natuzzi (NTZ), which lost 1.9% and 1.8% respectively.The gainers from the UK were led by biopharmaceutical company Akari Therapeutics (AKTX) and biotech firm Autolus Therapeutics (AUTL), which rose 11% and 4.7% respectively. They were followed by mining company BHP Group (BHP) and telecommunications operator Vodafone Group (VOD), which were up 2.7% and 2.2% respectively.The decliners from the UK and Ireland were led by biopharmaceutical company Mereo BioPharma Group (MREO) and software firm Endava (DAVA), which fell 3.1% and 2.9% respectively. They were followed by biopharmaceutical company Biodexa Pharmaceuticals (BDRX) and educational publisher Pearson (PSO), which were down 2.1% and 1.4% respectively.

$AKTX$ASND$AUTL$BDRX$BHP$DAVA$DBVT$EDAP$EVAX$MREO$NOK$NTZ$PSO$SAP$TRVG$VOD
Asia Markets

European Equities Traded in the US as American Depositary Receipts Heading Lower in Thursday Trading

European equities traded in the US as American depositary receipts were tracking lower late Thursday morning, losing 0.87% to 1,830.89 on the S&P Europe Select ADR Index.From continental Europe, the gainers were led by medical device maker EDAP TMS (EDAP) and accommodations booking company trivago (TRVG), which advanced 12% and 8%, respectively. They were followed by internet advertising firm Criteo (CRTO) and software company SAP (SAP), which increased 3.8% and 3.5%, respectively.The decliners from continental Europe were led by telecommunications company Nokia (NOK) and petroleum refiner Equinor (EQNR), which fell 4.4% and 4.3%, respectively. They were followed by semiconductor company Sequans Communications (SQNS) and pharmaceutical company Ascendis Pharma (ASND), which were down 2.7% and 2.3% respectively.The gainers from the UK were led by biopharmaceutical companies Akari Therapeutics (AKTX) and Biodexa Pharmaceuticals (BDRX), which rose 5.3% and 3.8% respectively. They were followed by communications company WPP (WPP) and hospitality company InterContinental Hotels Group (IHG), which were up 2.7% and 2.3% respectively.The decliners from the UK and Ireland were led by pharmaceutical company Silence Therapeutics (SLN) and biopharmaceutical company Bicycle Therapeutics (BCYC), which lost 4.9% and 3.2% respectively. They were followed by biotech firm Autolus Therapeutics (AUTL) and oil and gas company Shell (SHEL), which dropped 2.7% and 2.6% respectively.

$AKTX$ASND$AUTL$BCYC$BDRX$CRTO$EDAP$EQNR$IHG$NOK$SAP$SHEL$SLN$SQNS$TRVG$WPP
Asia Markets

European Equities Traded in the US as American Depositary Receipts Edge Higher in Wednesday Trading

European equities traded in the US as American depositary receipts were higher late Wednesday morning, edging up 0.12% to 1,808.88 on the S&P Europe Select ADR Index.From continental Europe, the gainers were led by oil and gas firm Eni (E) and semiconductor firm Sequans Communications (SQNS), which rose 1.8% and 1.5% respectively. They were followed by 3D printer company Materialise (MTLS) and internet advertising firm Criteo (CRTO), which were up 1.1% and 0.7% respectively.The decliners from continental Europe were led by telecommunications company Nokia (NOK) and Ascendis Pharma (ASND), which fell 4.1% and 4% respectively. They were followed by medical device maker EDAP TMS (EDAP) and biotech firm Evaxion (EVAX), which were down 1.8% and 0.2% respectively.The gainers from the UK were led by mining company BHP Group (BHP) and pharmaceutical company Silence Therapeutics (SLN), which advanced 3% and 2.9% respectively. They were followed by utilities company National Grid (NGG) and telecommunications operator Vodafone (VOD), which increased 2.8% and 1.6% respectively.The decliners from the UK and Ireland were led by Akari Therapeutics (AKTX) and Biodexa Pharmaceuticals (BDRX), which dropped 3.8% and 3.4% respectively. They were followed by alcoholic beverage company Diageo (DEO) and hospitality company InterContinental Hotels Group (IHG), which lost 1.8% and 1.4% respectively.

$AKTX$ASND$BDRX$BHP$CRTO$DEO$E$EDAP$EVAX$IHG$MTLS$NGG$NOK$SLN$SQNS$VOD
Asia Markets

European Equities Traded in the US as American Depositary Receipts Sharply Lower in Tuesday Trading

European equities traded in the US as American depositary receipts were falling sharply late Tuesday morning, dropping 1.15% to 1,812.72 on the S&P Europe Select ADR Index.From continental Europe, the gainers were led by petroleum refiner Equinor (EQNR) and internet browser company Opera (OPRA), which rose 2.7% and 1.7% respectively. They were followed by 3D printer company Materialise (MTLS) and medical device maker EDAP TMS (EDAP), which were up 1.2% each.The decliners from continental Europe were led by biopharmaceutical company argenx (ARGX) and pharmaceutical company Novo Nordisk (NVO), which fell 3% and 2.8% respectively. They were followed by biotech firm Evaxion (EVAX) and pharmaceutical company Ascendis Pharma (ASND), which were down 2.7% each.The gainers from the UK were led by biopharmaceutical company Akari Therapeutics (AKTX) and software firm Endava (DAVA), which advanced 6.4% and 2.7% respectively. They were followed by education company Pearson (PSO) and pharmaceutical company Silence Therapeutics (SLN), which increased 1.2% and 0.9% respectively.The decliners from the UK and Ireland were led by biopharmaceutical companies Biodexa Pharmaceuticals (BDRX) and NuCana (NCNA), which dropped 8.7% and 3.2% respectively. They were followed by biopharmaceutical company Mereo BioPharma Group (MREO) and cruise line operator Carnival (CUK), which lost 2.3% and 2.2% respectively.

$AKTX$ARGX$ASND$BDRX$CUK$DAVA$EDAP$EQNR$EVAX$MREO$MTLS$NCNA$NVO$OPRA$PSO$SLN
Asia Markets

European Equities Traded in the US as ADRs Rise in Tuesday Trading

European equities traded in the US as American depositary receipts rose late Tuesday morning with the S&P Europe Select ADR Index gaining 0.3% to 1,844.78.From continental Europe, the gainers were led by biopharmaceutical company Grifols (GRFS) and internet browser company Opera (OPRA), which rose 3.1% and 2.9%, respectively. They were followed by pharmaceutical company Novo Nordisk (NVO) and semiconductor company Sequans Communications (SQNS), which were up 2.3% and 1.6%, respectively.The decliners from continental Europe were led by petroleum refiner Equinor (EQNR) and biotech firm Evaxion (EVAX), which fell 2.5% and 1.2%, respectively. They were followed by oil and gas company Eni (E) and pharmaceutical company Ascendis Pharma (ASND), which were down 1% and 0.5%, respectively.The gainers from the UK were led by biopharmaceutical companies Bicycle Therapeutics (BCYC) and Biodexa Pharmaceuticals (BDRX), which advanced 6.2% and 4.2%, respectively. They were followed by biopharmaceutical company NuCana (NCNA) and cruise line operator Carnival (CUK), which increased 3.4% and 3%, respectively.The decliners from the UK and Ireland were led by biotech firm Trinity Biotech (TRIB) and pharmaceutical company Silence Therapeutics (SLN), which dropped 1.7% and 1.5%, respectively. They were followed by tobacco company British American Tobacco (BTI) and oil and gas company Shell (SHEL), which were off 1.4% and 1.1%, respectively.

$ASND$BCYC$BDRX$BTI$CUK$E$EQNR$EVAX$GRFS$NCNA$NVO$OPRA$SHEL$SLN$SQNS$TRIB
Asia Markets

European Equities Traded in the US as American Depositary Receipts Rise in Friday Trading

European equities traded in the US as American depositary receipts were tracking higher late Friday morning, gaining 0.75% to 1,828.19 on the S&P Europe Select ADR Index, which is up 4% for the week.From continental Europe, the gainers were led by biopharmaceutical company Cellectis (CLLS) and lender Banco Bilbao Vizcaya Argentaria (BBVA), which climbed 6.6% and 2% respectively. They were followed by health-tech conglomerate Royal Philips (PHG) and biopharmaceutical company Grifols (GRFS), which rose 1.6% and 1.4% respectively.The decliners from continental Europe were led by biopharmaceutical company DBV Technologies (DBVT) and internet browser company Opera (OPRA), which fell 2.7% and 2.5% respectively. They were followed by internet advertising firm Criteo (CRTO) and pharmaceutical company Ascendis Pharma (ASND), which dropped 1.8% and 1.4% respectively.The gainers from the UK were led by biotech firm Autolus Therapeutics (AUTL) and biopharmaceutical company Biodexa Pharmaceuticals (BDRX), which advanced 5.1% and 4.3% respectively. They were followed by biotech company Trinity Biotech (TRIB) and medical device maker Smith & Nephew (SNN), which were up 2.3% and 2.1% respectively.The decliners from the UK and Ireland were led by pharmaceutical company Silence Therapeutics (SLN) and software firm Endava (DAVA), which lost 4.6% and 2.1% respectively. They were followed by biopharmaceutical companies Akari Therapeutics (AKTX) and Amarin (AMRN), which were down 1.9% and 1.5% respectively.

$AKTX$AMRN$ASND$AUTL$BBVA$BDRX$CLLS$CRTO$DAVA$DBVT$GRFS$OPRA$PHG$SLN$SNN$TRIB
Asia Markets

European Equities Traded in the US as American Depositary Receipts Decline in Thursday Trading

European equities traded in the US as American depositary receipts were tracking lower late Thursday morning, declining 0.48% to 1,803.06 on the S&P Europe Select ADR Index.From continental Europe, the gainers were led by biotech firm Evaxion (EVAX) and pharmaceutical company Ascendis Pharma (ASND), which advanced 4% and 3.1% respectively. They were followed by oil and gas company Eni (E) and telecommunications company Nokia (NOK), which increased 3% and 0.3% respectively.The decliners from continental Europe were led by biopharmaceutical company Grifols (GRFS) and software firm SAP (SAP), which dropped 4.4% and 3.8% respectively. They were followed by internet browser company Opera (OPRA) and biopharmaceutical company Cellectis (CLLS), which lost 3% and 2.5% respectively.The gainers from the UK were led by biopharmaceutical company NuCana (NCNA) and oil and gas company BP (BP), which rose 5.5% and 2.2% respectively. They were followed by biotech firm Trinity Biotech (TRIB) and biopharmaceutical company Amarin (AMRN), which were up 1.8% and 0.5% respectively.The decliners from the UK and Ireland were led by biopharmaceutical company Biodexa Pharmaceuticals (BDRX) and pharmaceutical company Silence Therapeutics (SLN), which fell 12% and 4.3% respectively. They were followed by communications company WPP (WPP) and cruise line operator Carnival (CUK), which were down 3.7% and 3.3% respectively.

$AMRN$ASND$BDRX$BP$CLLS$CUK$E$EVAX$GRFS$NCNA$NOK$OPRA$SAP$SLN$TRIB$WPP