Baird downgraded Karyopharm Therapeutics (KPTI) to neutral from outperform while adjusting its price target to $3 from $15.
Shares slumped 71% as intraday trading volume jumped to over 15.0 million from a daily average of about 568,000.
GoDaddy (GDDY) shares sank 20% amid heavy trading after the company narrowed its full year 2026 revenue guidance.
More than 3.66 million shares of the company traded intraday compared with a daily average of about 2.45 million.
Coinbase Global (COIN) reported a Q2 loss and a drop in year-over-year revenue late Thursday. Rosenblatt Securities adjusted the company's price target to $200 from $240 while maintaining its buy rating.
Shares of Coinbase slumped 9.5% as intraday trading volume climbed to over 13.8 million from the stock's daily average of about 8.45 million.
Price: $148.05, Change: $-15.53, Percent Change: -9.49%