FINWIRES · TerminalLIVE
FINWIRES

Ascendis Has Capacity To Execute Alone After Termination of Novo Nordisk Collaboration, Wedbush Says

By

Ascendis Pharma (ASND) share selloff on Tuesday after the termination of its collaboration agreement with Novo Nordisk (NVO) was likely an over-reaction, with additional pressure from weakness in the biotech sector, Wedbush said in a note Wednesday, adding it believes the company has the capacity to execute alone.

Ascendis said Monday it will regain exclusive rights to some drug treatments for metabolic and cardiovascular diseases, including obesity, after terminating a 2024 collaboration deal with Novo. In particular, all rights to once-monthly TransCon Semaglutide obesity treatments will revert to Ascendis upon termination, the company said.

Wedbush said that Ascendis now has "proven expertise" in the development of three products through US Food and Drug Administration approvals for metabolic disorders, and it should "have sufficient capacity to move the TransCon Semaglutide and additional programs for metabolic/cardiovascular diseases forward efficiently."

The investment firm also said that, after a discussion with Ascendis' management about the decision to terminate the Novo collaboration, it still sees the "TransCon technology platform as supporting ASND's strong long-term growth potential."

Wedbush has an outperform rating on Ascendis and a $327 price target.

Price: $239.90, Change: $+0.13, Percent Change: +0.05%

What else is happening in Wire?

Wire

Tempest Therapeutics Gains Option to License New In-Body CAR-T Technology From Senlang

Tempest Therapeutics (TPST) signed an exclusive option agreement with China's Hebei Senlang Biotechnology to license a clinical-stage technology that delivers CAR-T cancer treatments directly inside the body, along with a portfolio of related drug candidates.The portfolio includes an early-stage treatment that targets two proteins linked to multiple myeloma and is now being tested in a phase 1 study, Tempest said Tuesday in a statement. Other candidates in the group are aimed at blood cancers and autoimmune diseases, the company said.Tempest said it will continue to evaluate phase 1 results with Senlang during the option period.The company also disclosed in a regulatory filing that it raised about $2.5 million last week through a private placement of prefunded and common stock warrants.Tempest shares rose 35% in after-hours trading.

$TPST
Wire

Top Cryptocurrencies Fall; Bitcoin Drops Below $76,000

Top cryptocurrencies fell Tuesday, with Bitcoin (BTC-USD) dropping below $76,000.The CoinDesk Market Index, which tracks dozens of digital assets including Bitcoin, fell 5% in the past 24 hours. The Nasdaq 100 shed 0.8%, the S&P 500 lost 0.5%, and the Dow Jones Industrial Average declined 0.7%.Bitcoin fell 4.1% to $75,847, according to CoinMarketCap data. The most popular cryptocurrency's 24-hour trading volume rose 42% to $39.6 billion.Ethereum (ETH-USD), the second-largest digital asset by market value, declined 5.5% to $2,404.XRP (XRP-USD) lost 11%, BNB (BNB-USD) slumped 1.2%, and Solana (SOL-USD) shed 5.4%. Dogecoin (DOGE-USD) dropped 4.8%, and Cardano (ADA-USD) decreased 7.3%.The total market value of the cryptocurrency industry fell 4.1% in the past 24 hours to $2.58 trillion, with trading volume rising 31% to $103.1 billion.Price: $75891.45, Change: $-2289.88, Percent Change: -2.93%

$ADA-USD$BNB-USD$BTC-USD$DOGE-USD$ETH-USD$SOL-USD$XRP-USD
Wire

Update: PBF Energy Shares Rise After Pricing $500 Million Exchangeable Notes Offering

(Updates with the latest stock price movement in the headline and the first paragraph.)PBF Energy (PBF) shares rose 6.1% on Tuesday, a day after the company said that, along with its PBF Finance unit, it priced $500 million worth of zero-rated exchangeable notes due 2032 in a private offering.The deal is expected to close on Sept. 17.PBF also granted the initial purchasers a 13-day option to buy up to an additional $50 million of notes, it said.The initial exchange rate is $96.80 per share, according to the company.Net proceeds, estimated at $485 million to $533.6 million, will be used to cover the cost of certain associated derivative transactions, repay other debt, and for general corporate purposes, PBF said.Price: $74.60, Change: $+4.20, Percent Change: +5.97%

$PBF