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FINWIRES

European Stocks Fall Sharply in Monday Trading as Hopes of Middle East Ceasefire Dim

-- European markets were tracking lower Monday as investors are discouraged by reports that Tehran will not participate in pending peace-talks with Washington, and that President Donald Trump said an extension of the two-week ceasefire with Iran is "highly unlikely" and that the Strait of Hormuz would remain blocked until an agreement is finalized.

The Stoxx Europe was falling 1%, Germany's DAX was dropping 1.2%, the FTSE 100 was down 0.7%, France's CAC was declining 1.2%, and the Swiss Market Index was moving 1.5% lower.

Rising oil prices lifted energy stocks in Monday trading as BP and Shell gained 3% and 2.4% respectively in London. RWE increased 2.3% in Frankfurt, TotalEnergies was rising close to 2% in Paris, while Eni and Equinor were up 2.8% and 2.3% respectively in Milan and Oslo.

And in corporate news, Novo Nordisk reported Monday "positive" topline results from its Phase 3 HIBISCUS trial, with etavopivat meeting both primary endpoints in sickle cell disease, significantly reducing vaso-occlusive crises and improving haemoglobin levels versus placebo.

Novo Nordisk said it plans to seek initial regulatory approval for the drug in the second half of 2026, positioning it as a potential first-in-class treatment for a disease affecting millions worldwide.

Shares of the Danish pharmaceutical company were down 1% in Copenhagen.

BHP and Mitsubishi Development have started a review of their coal and other mining assets in Queensland over concerns about the Australian state's royalty demands, Bloomberg reported Monday, citing unnamed people familiar with the matter.

The two companies are equal partners in the BHP Mitsubishi Alliance joint venture, which returned no profit to BHP in the six months ending Dec. 31, the report said.

BHP did not immediately reply to' request for comment.

Shares of BHP lost 1.6% in London.

Sanofi said Saturday its Nuvaxovid COVID-19 vaccine met the primary endpoint of a phase 4 trial by demonstrating a statistically lower probability of side effects compared with Moderna's newest mRNA vaccine.

Severe systemic symptoms disrupting daily activities occurred in less than 10% of Nuvaxovid patients compared to one in five for the Moderna shot, while severe injection site reactions were over 75% less frequent, Sanofi said.

Shares of the French pharmaceutical company were off 0.4% in Paris.

AstraZeneca said Monday its pivotal phase 3 study of tozorakimab demonstrated a "significant" reduction in the annual rate of moderate-to-severe chronic obstructive pulmonary disease, or COPD, exacerbations in trial participants.

The population comprised former smokers, current smokers and participants throughout all blood eosinophil counts and all stages of lung function severity, according to the company.

Shares of the British pharmaceutical company were losing 0.8% in London.

GSK said Monday China's National Medical Products Administration has approved Blenrep in combination with bortezomib and dexamethasone to treat certain relapsed or refractory multiple myeloma patients.

The approval covers adults with relapsed or refractory multiple myeloma who have received at least one prior line of therapy.

Shares of GSK were off 0.1% in London.

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Insider Trading

ブレイズ・ホールディングスのインサイダーが28万1489ドル相当の株式を売却したことが、最近のSEC提出書類で明らかになった。

最高財務責任者(CFO)のハーミンダー・セーミ氏は、2026年4月20日にブレイズ・ホールディングス(BZAI)の株式123,460株を281,489ドルで売却しました。SECへのフォーム4提出後、セーミ氏は同社の普通株式合計381,600株を保有しており、そのうち381,600株は直接保有しています。 SEC提出書類:https://www.sec.gov/Archives/edgar/data/1871638/000204838326000001/xslF345X05/wk-form4_1776879377.xmlPrice: $2.14, Change: $-0.01, Percent Change: -0.23%

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Sectors

セクター最新情報:水曜午後の消費関連株はまちまち

水曜午後の消費関連株はまちまちの動きとなり、ステート・ストリート・コンシューマー・ステープルズ・セレクト・セクターSPDR ETF(XLP)は0.3%上昇、ステート・ストリート・コンシューマー・ディスクレショナリー・セレクト・セクターSPDR ETF(XLY)は0.1%下落した。 企業ニュースでは、フィリップ・モリス・インターナショナル(PM)の株価が、市場予想を上回る第1四半期決算を発表したことを受け、6%以上急騰した。 AT&T(T)は水曜日に予想を上回る第1四半期決算を発表し、通期業績見通しを据え置いた。AT&Tの株価は0.3%下落した。 ベスト・バイ(BBY)の株価は、コリー・バリー最高経営責任者(CEO)が第3四半期末をもって退任し、最高顧客・製品・フルフィルメント責任者(CCO)のジェイソン・ボンフィグ氏が後任に就任すると発表したことを受け、4.8%下落した。

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Australia

正午の上昇率上位銘柄

Axe Compute(AGPU)は水曜日、米国ティア3データセンターにNVIDIA(NVDA)B300グラフィックス処理ユニット2,304基とストレージインフラストラクチャを導入する2億6,000万ドルのエンタープライズインフラストラクチャ契約を受注したと発表した。 株価は88%急騰し、日中取引高は1日平均約192万株から7,480万株以上に急増した。 GE Vernova(GEV)は水曜日、第1四半期の利益と売上高が前年同期比で増加したと発表し、通期売上高見通しを引き上げた。 株価は13%上昇し、日中取引高は1日平均約264万株から312万株以上に増加した。 トロ(TORO)は、5月4日時点の株主名簿に記載されている株主に対し、1株当たり0.90ドルの特別配当を6月5日に支払うと発表した。 株価は正午過ぎに84%急騰し、7.31ドルとなった。日中取引量は、1日平均約5万5000株から1470万株以上に急増した。Price: $9.02, Change: $+4.14, Percent Change: +84.73%

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