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$EXEL

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Wire

Exelixis Q2 Adjusted Earnings, Revenue Rise; Shares Drop After Hours

Exelixis (EXEL) reported Q2 adjusted earnings late Wednesday of $0.91 per diluted share, up from $0.75 a year earlier.Analysts polled by FactSet expected $0.85.Revenue in the three months ended June 30 rose to $628.7 million from $568.3 million a year earlier.Analysts projected $636.4 million.The company cut full-year revenue guidance to $2.5 billion to $2.55 billion from the prior forecast of $2.525 billion to $2.625 billion.Analysts project $2.596 billion.Exelixis shares fell 5.2% in after-hours trading.

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Sectors

Sector Update: Healthcare Stocks Gain Thursday Afternoon

Healthcare stocks were higher Thursday afternoon, with the NYSE Healthcare Index rising 2% and the State Street Health Care Select Sector SPDR ETF (XLV) adding 2.1%.The iShares Biotechnology ETF (IBB) advanced 1.6%.In corporate news, AbbVie (ABBV) and other healthcare stocks were rising after the Trump administration reportedly proposed a new rule to curb hospital drug markups in Medicare. According to The Associated Press, the rule targets hospitals in the 340B program, which allows them to buy outpatient drugs at reduced prices for low-income patients but often bill insurers at higher rates and keep the difference. AbbVie rose 3.2%, Johnson & Johnson (JNJ) was up 2.9%, Bristol-Myers Squibb (BMY) gained 2.4%, and Merck (MRK) added 2.2%.Ensign (ENSG) shares rose 1.7% after the company said it has purchased the real estate and operations of two skilled nursing facilities in Texas.Exelixis (EXEL) offers balanced risk-reward ahead of several key catalysts, with its Zanzalintinib therapy well positioned for success in a non-clear cell renal cell carcinoma, or nccRCC, trial readout in the second half of 2026 that could lift the stock, UBS Securities said. The firm raised its price target on Exelixis to $52 from $43 and reiterated its neutral rating. Exelixis shares added 1.8%.

$ABBV$BMY$ENSG$EXEL$JNJ$MRK
Wire

Exelixis Faces Balanced Risk-Reward Ahead of Key Catalysts, UBS Says

Exelixis (EXEL) offers balanced risk-reward ahead of several key catalysts, with its Zanzalintinib therapy well positioned for success in a non-clear cell renal cell carcinoma, or nccRCC, trial readout in the second half of 2026 that could lift the stock, UBS Securities said.The brokerage said Zanzalintinib's expansion into additional indications will be critical to maintaining Exelixis' value after Cabometyx loses exclusivity. Even if the nccRCC readout is positive, UBS said there remains debate over whether Zanzalintinib can outperform Cabometyx in renal cell carcinoma.The firm also said the therapy's potential launch in metastatic colorectal cancer remains another important catalyst, with the US Food and Drug Administration's target action date for the company's new drug application set for Dec. 3.UBS models Q2 product revenue of $569 million, below the Visible Alpha consensus estimate of $584 million. The brokerage maintained its 2026 product revenue estimate of $2.3 billion, compared with the Visible Alpha consensus of $2.4 billion.The firm raised its price target on Exelixis to $52 from $43 and reiterated its neutral rating.Shares of Exelixis were up 3% in Thursday trading.Price: $55.59, Change: $+1.63, Percent Change: +3.02%

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Wire

UBS Adjusts Price Target on Exelixis to $52 From $43, Maintains Neutral Rating

Exelixis (EXEL) has an average rating of hold and mean price target of $136.11, according to analysts polled by FactSet.(covers equity, commodity and economic research from major banks and research firms in North America, Asia and Europe. Research providers may contact us here: https://finwires.com/en/contact)Price: $55.31, Change: $+1.35, Percent Change: +2.50%

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Insider Trading

Exelixis Insider Sold Shares Worth $1,745,050, According to a Recent SEC Filing

Christopher J. Senner, Executive Vice President and Chief Financial Officer, on May 15, 2026, sold 34,901 shares in Exelixis (EXEL) for $1,745,050. Following the Form 4 filing with the SEC, Senner has control over a total of 955,040 common shares of the company, with 952,317 shares held directly and 2,723 controlled indirectly.SEC Filing:https://www.sec.gov/Archives/edgar/data/939767/000093976726000067/xslF345X05/wk-form4_1779231521.xml

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Wire

Exelixis Seen Trading Steady on Modest Drug Growth, RBC Says

Exelixis (EXEL) shares are likely to trade in line with peers as its cancer drug cabozantinib, used in kidney cancer and neuroendocrine tumors, continues to post steady growth, while most near-term catalysts are already reflected in the stock, RBC Capital Markets said Wednesday in a report.Exelixis' 2026 outlook assumes continued cabozantinib growth, though it still has concerns about erosion in renal-cell carcinoma and limited chances for further gains in neuroendocrine tumors, the report said. Cabozantinib revenue in Q1 rose about 1.5% from the previous quarter and 8% from a year earlier, helped by the highest number of patient starts to date, RBC said.Exelixis is broadening development of zanzalintinib, its next-generation cancer therapy, through new studies and combination regimens, RBC said. Still, a meaningful revenue contribution from zanzalintinib isn't expected until 2027, even with a potential approval in late-line colorectal cancer this year, the report said.RBC maintained its sector perform rating on Exelixis stock with a price target of $43.Price: $47.13, Change: $+2.71, Percent Change: +6.10%

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