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3 stories mentioning EPRX.TOUpdated 36d ago

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Mining & Metals

Eupraxia Pharmaceuticals Q1 Loss Narrows

Eupraxia Pharmaceuticals' (EPRX.TO) first-quarter loss narrowed, the company said after trade on Tuesday.The company, which is using its Diffusphere technology to optimize localized, controlled drug delivery for diseases with significant unmet need, reported a loss of US$12.7 million, or US$0.23 per share, from a loss of US$6.8 million or US$0.21, for the prior year period. Analysts polled by FactSet had expected a loss of US$0.19 per share.The increased loss was primarily due to higher research and development costs as a result of doubling the size of the RESOLVE Part 2 trial and general and administrative costs, a statement noted.Eupraxia reported cash of US$58.5 million and short-term investments of $80.4 million as of March 31, up from a cash balance of $80.6 million at the end of the fourth quarter of 2025. These funds are being used to fund clinical trials.The company anticipates that existing cash reserves, and proceeds from the future exercise of in-the-money warrants, will be sufficient to fund it into the second half of 2028."The clinical data reported this quarter further reinforces the potential for EP-104GI to become an important new treatment for Eosinophilic Esophagitis (EoE)," said chief executive Dr. James Helliwell. "With the capital from the recent financing, we are excited to continue development of EP-104GI in EoE and accelerate additional clinical programs in new indications within the GI field, where we believe that EP-104GI has the opportunity to work due to the Diffusphere's ability to provide hyper-targeted delivery into diseased areas over a long period of time without the typical systemic exposure profile."Eupraxia shares closed up $0.39, to $10.51 on the Toronto Stock Exchange.

$EPRX.TO
Mining & Metals

Eupraxia Pharmaceuticals Appointing Dr. Jeymi Tambiah as Chief Medical Officer With Retirement of Dr. Mark Kowalski, Current CMO

$EPRX.TO
Mining & Metals

Eupraxia Reports Latest 36-Week Results From Resolve Trial

Eupraxia Pharmaceuticals (EPRX.TO) Tuesday reported the latest 36-week results for the highest dose from the dose escalation portion of the Resolve trial.Patients in Cohort 9 demonstrated a "robust" response in both tissue health and symptom response compared to their baseline levels, the company said. Clinical remission in symptoms was maintained in 66% of the patients in Cohort 9 at week 36. This level of remission was first achieved at week 8 and was maintained through 36 weeks, a statement added.Phase 1b/2a of the Resolve trial is a multicenter, dose-escalation study testing the efficacy and safety of Eupraxia's EP-104GI in adults with active eosinophilic esophagitis (EoE.) The treatment is administered as a single dose via four to 20 esophageal wall injections, and continues to be well tolerated by patients receiving the drug."This data is consistent with the compelling results we observed at earlier timepoints at this dose level, highlighting the potential to achieve both strong and durable responses after a single administration of EP-104GI. We are also reassured by the excellent safety outcomes across all doses in the trial as we continue to observe no indication of drug related SAEs or spikes in glucose or cortisol," said chief executive Dr James Halliwell.The top-line data from the Phase 2b part of the Resolve trial is expected in the fourth quarter of this year.Eupraxia shares closed up $0.16, to $9.90, on Monday, on the Toronto Stock Exchange.

$EPRX.TO

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