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ASX:IMU

2 stories mentioning ASX:IMUUpdated 10m ago

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Asia

Imugene Says Additional Patient in BTKi Group of Azer-Cel Phase 1b Study Achieves Complete Response, Shares Surge 26%

Imugene (ASX:IMU) said additional patient data from the concurrent Bruton's tyrosine-protein inhibitor (BTKi) group of its azer-cel therapy candidate phase 1b study showed a complete response, according to a Friday Australian bourse filing.Azer-cel is an off-the-shelf allogeneic CAR T cell therapy targeting the CD19 protein to treat blood cancers.The mantle cell lymphoma (MCL) patient was the first one treated in the study and had previously failed BTKi therapy. The patient achieved a complete response at the day 28 assessment.To date, four patients have been dosed in the concurrent BTKi group, and two of these patients are evaluable, both achieving a complete response.Its shares surged 26% in recent trading on Wednesday.

ASX:IMU
Asia

Imugene Reports 81% Overall Response Rate in Azer-Cel Phase 1b Study, Shares Surge 22%

Imugene (ASX:IMU) said data from its azer-cel Phase 1b abstract, published on the American Society of Clinical Oncology (ASCO) website, showed an overall response rate (ORR) of 81% among 16 evaluable patients, according to a Friday Australian bourse filing.The company said Azer-cel, an off-the-shelf allogeneic CAR T cell therapy targeting CD19 to treat blood cancers, showed responses across multiple lymphoma and leukemia subtypes, including a 60% response rate in diffuse large B-cell lymphoma (DLBCL) and a 100% response rate in marginal zone lymphoma (MZL).The company's shares rose 22% in recent Friday trade.

ASX:IMU

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