$ANL

Adlai Nortye's KRAS Opportunity Further Validated by GSK-Hutchmed Deal, Oppenheimer Says

Adlai Nortye (ANL) stands to benefit from the GSK (GSK)-Hutchmed (HCM) deal, which validates growing interest in targeted KRAS therapies, Oppenheimer said in a note emailed Friday.Hutchmed said Thursday its unit licensed rights to GSK to develop and commercialize experimental cancer treatment HMPL-A830 outside Greater China.HMPL-A830 is an EGFR-targeted antibody-drug conjugate carrying a KRAS inhibitor payload. The deal highlights increasing interest in targeted approaches that aim to improve the therapeutic index of RAS-pathway inhibition, Oppenheimer analysts said.Adlai Nortye's approach is differentiated, with AN9025 already in the clinic and data expected in H1 2027. AN4035 uses a pan-RAS(ON) inhibitor payload with a CEACAM5-targeting antibody, which could provide advantages in breadth, durability, and target selection, the analysts added.The deal should improve "investor awareness of comparable RAS-focused platforms and reinforce the strategic value embedded within Adlai Nortye's differentiated RAS franchise," the analysts said.Oppenheimer has an outperform rating and a $32 price target on Adlai Nortye.Price: $15.14, Change: $+0.39, Percent Change: +2.64%

Cantor Fitzgerald Initiates Adlai Nortye at Overweight

Adlai Nortye (ANL) has an average rating of buy and mean price target of $28.60, according to analysts polled by FactSet.(covers equity, commodity and economic research from major banks and research firms in North America, Asia and Europe. Research providers may contact us here: https://finwires.com/en/contact)

Oppenheimer Initiates Adlai Nortye With Outperform Rating, $32 Price Target