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Japanese shares tumbled at Thursday's market open, tracking losses in US equity-index futures following renewed hostilities between the US and Iran that jolted investor confidence.The Nikkei 225 fell 541.3 points or 0.8% to open at 67,860.84.The overnight clashes, which involved Kuwait and Bahrain, mark the most significant escalation since a ceasefire took effect in early April and threaten to undermine ongoing US-Iran talks over extending the truce and reopening the Strait of Hormuz.Meanwhile, Dallas Federal Reserve President Lorie Logan signaled that US rate hikes may be needed later this year, while Bank of Japan Governor Kazuo Ueda suggested a rate hike this month is likely if inflation risks outweigh potential economic harm from the Middle East crisis.Ueda stated that as long as regional turmoil subsides and price growth steadily approaches the 2% target, the BOJ will raise borrowing costs at an appropriate pace.