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Research Alert: Iclr: Q4 2025 Results Mixed After Long Delay; 2026 Guidance Headwinds

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CFRA, an independent research provider, has providedwith the following research alert. Analysts at CFRA have summarized their opinion as follows:

ICON reported challenging Q4 results with sales of $2.11B (+2.5% Y/Y, $130M above consensus) but adjusted EPS of $2.52 fell $0.59 short of estimates and declined 26.5%. Full-year 2025 sales of $8.25B rose just 0.8%, while adjusted EBITDA margin contracted meaningfully to 18.6% (-180 bps), reflecting industry headwinds including elevated cancellations and pricing pressure. A bright spot was strong bookings momentum with $3.2B in Q4 gross wins supporting a robust 1.36 book-to-bill ratio, while the completed accounting investigation resulted in minimal revenue restatements of 0.8%-1.1% for 2023-2024 with no operational impact. For 2026, ICLR guided to revenue of $7.85B-$8.15B and EPS of $10.00-$11.00, representing declines of about 3% and 16%, respectively, at the midpoint. The guidance reflects continued near-term margin pressure and operational challenges, in our view, though management expressed confidence in large pharma spending recovery and improving biotech funding conditions.

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