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Research Alert: CFRA Maintains Hold Opinion On Shares Of Alnylam Pharmaceuticals, Inc

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-- CFRA, an independent research provider, has providedwith the following research alert. Analysts at CFRA have summarized their opinion as follows:

We lower our target price to $319 from $340 based on our NPV analysis. We raise our 2026 EPS forecast to $9.32 from $8.02, and maintain our 2027 EPS estimate at $11.97. Alnylam (ALNY) reported a strong first quarter for 2026, exceeding both earnings and revenue estimates. The company achieved a significant milestone, in our view, surpassing $1B in quarterly product revenue for the first time in its history. This performance was largely due to the successful commercial launch and uptake of AMVUTTRA for ATTR-CM. While international TTR revenue grew 35% year-over-year in Q1, it declined by $7 million from the previous quarter. This was mainly due to a previously announced price adjustment in Germany following the ATTR-CM launch. We think a significant portion of ALNY's revenue is concentrated in its TTR franchise, which could be a vulnerability if new competitors or unforeseen challenges emerge.

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