FINWIRES · TerminalLIVE
FINWIRES

Genmab Says Subgroup Data for Follicular Lymphoma Treatment Shows 'Sustained' Efficacy Benefits

By

Genmab (GMAB) said Thursday that new data from a post-hoc subgroup analysis of its phase 3 Epcore FL-1 trial showed that in adult patients with relapsed or refractory follicular lymphoma, epcoritamab in combination with rituximab and lenalidomide showed "consistent and sustained efficacy benefits" across clinically relevant subgroups.

The new data included a Follicular Lymphoma International Prognostic Index score of 0-2 versus 3-5 previously, progression of disease less than or equal to two years from the date of initial frontline therapy POD24, and patient fitness, the company said.

The safety profile of epcoritamab in combination with rituximab and lenalidomide was "manageable" across all patient subgroups and consistent with that observed in the overall trial population, with no new safety signals identified, the company added.

The results will be presented during an oral presentation at the European Hematology Association 2026 Congress held in Stockholm, the company said.

Price: $24.94, Change: $+0.45, Percent Change: +1.82%

Related Articles

Wire

Lendlease Group Reaffirms IDC Business Fiscal 2026 Earnings Guidance; Shares Jump 3%

Lendlease Group (ASX:LLC) said its fiscal 2026 earnings per security guidance for the IDC business was maintained at AU$0.28 to AU$0.34 per share, subject to targeted completions in the fiscal year, according to a Thursday Australian bourse filing.Following AU$4.7 billion of new Australian projects secured in the half year, the Group is working to unlock over AU$10 billion of balance sheet positions at Rozelle Bay, Sydney, and the Brisbane Athlete Village.New work secured for construction in fiscal 2026 is expected to be around AU$6.5 billion, supported by social infrastructure, defense, transport, and data centers, the company said. Backlog revenue as of June 30 is expected to be around AU$8 billion, supporting earnings momentum into fiscal 2027.The company's asset recycling program continues to progress with a number of well-advanced transactions now likely to be completed in early fiscal 2027, per the filing. Due to the timing of transactions and more challenging market conditions, underlying group gearing in fiscal 2026 is anticipated to be in the mid-30% range.Lendlease Group's shares rose past 3% in recent trading on Thursday.

$ASX:LLC
Wire

Oxford Industries Fiscal Q1 Adjusted Earnings, Revenue Fall; Q2 Guidance Set

Oxford Industries (OXM) reported fiscal Q1 adjusted earnings late Wednesday of $1.39 per diluted share, down from $1.82 a year earlier.Analyst surveyed by FactSet expected $1.29.Revenue for the three months ended May 2 was $391.4 million, down from $392.9 million a year earlier.Analysts expected $391.8 million.For fiscal Q2, the company expects adjusted EPS of $1.20 to $1.40 on revenue of $380 million to $400 million. Analysts expect EPS of $1.46 on revenue of $413.9 million.For the full-year fiscal 2026, the company now expects adjusted EPS of $2.30 to $2.70 on revenue of $1.48 billion to $1.51 billion. Analysts expect EPS of $2.43 on revenue of $1.51 billion.Shares of the company were down over 12% during the after-hours.

$OXM
Wire

PureCycle Starts $250 Million Convertible Notes Offering, $145 Million Stock Sale

PureCycle Technologies (PCT) said late Wednesday it launched public offerings of $250 million of convertible senior notes due 2032 and $145 million of common shares.The company will grant underwriters 30-day overallotment options to buy up to an additional $37.5 million of the notes and $18.75 million of the shares.Net proceeds will be used to repurchase a portion of PureCycle's 7.25% green convertible notes due 2030, buy back additional green notes, and for general corporate purposes.PureCycle shares fell 11% in after-hours trading.

$PCT