Crude oil benchmarks jumped on Thursday, after reports emerged that Iran's Supreme Leader Ayatollah Mojtaba Khamenei banned the sending of weapons-grade uranium abroad.
Front-month Murban crude futures gained 2.6% to $105.92 per barrel, while Brent futures added 1.8% to $106.90/bbl.
Supporting prices, a Reuters report citing senior Iranian insiders, revealed that Khamenei issued a strict directive banning the export of the country's near-weapons-grade enriched uranium.
This counters a non-negotiable demand from US President Donald Trump, who had previously assured Israel that any comprehensive peace agreement would mandate the complete extraction of highly-enriched material from Iranian territory.
The severity of the global energy crisis resulting from the Iran war could yet push oil prices to $200 per barrel under a worst-case scenario, Wood Mackenzie said in a note.
The regional conflict is currently holding back more than 11 million barrels per day of Persian Gulf crude and condensate, alongside roughly 80 million tonnes per annum of liquefied natural gas representing 20% of the world's total gas supply.
However, on Wednesday, Trump said that negotiations with Iran are in their "final stages," raising optimism about a deal.
"Oil prices sold off heavily yesterday, with hopes growing once again for a potential US-Iran agreement," ING analysts said. Brent futures dropped more than 5% on Wednesday.
Analysts at ING noted that while the market has been burned by false breakthroughs before, it remains highly reactive due to the sheer significance of ongoing supply disruptions.
On the supply side, the US Energy Information Administration noted that US crude oil inventories decreased by 7.9 million barrels to 445 million barrels for the week ended May 15.