BioAge Labs (BIOA) said Tuesday it has dosed the first participant in its phase 2 trial of BGE-102 in adults with diabetic macular edema.
The trial will evaluate BGE-102, a once-daily oral NLRP3 inhibitor, both as monotherapy and as add-on to standard-of-care anti-VEGF therapy, with about 180 participants, the company said.
The primary endpoint is change in best-corrected visual acuity at week 12, BioAge Labs said.
Topline results are expected in H2 of 2027, the company added.
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