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Akeso's Ivonescimab Shows Overall Survival Benefit in Phase 3 Trial

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Akeso (HKG:9926) said its PD-1/VEGF bispecific antibody ivonescimab demonstrated a statistically significant and clinically meaningful overall survival benefit versus pembrolizumab in an interim analysis of a Phase 3 trial, according to a Thursday Hong Kong bourse filing.

The HARMONi-2 study met its pre-specified key secondary endpoint of overall survival in patients with locally advanced or metastatic non-small cell lung cancer with positive PD-L1 expression, the company said.

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