-- 据周四提交给澳大利亚证券交易所的文件显示,Radiopharm Theranostics(ASX:RAD)已完成美国2b期影像学试验的最后一名患者的给药。该试验旨在评估氟-18-RAD101在30名确诊为不同来源实体瘤复发性脑转移患者中的诊断性能。 该研究的主要目标是评估氟-18-RAD101阳性病灶与常规影像学检查(钆增强磁共振成像)所见病灶的一致性,研究对象为疑似复发性脑转移患者。 RAD101是一种新型成像小分子,靶向脂肪酸合成酶(FASN)。FASN是一种多酶蛋白,可催化脂肪酸合成,并在许多实体瘤中过度表达。
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