-- 根據週三提交給澳洲證券交易所的文件顯示，PYC Therapeutics（ASX：PYC）已獲得安全審查委員會的批准，可將候選藥物PYC-001推進至針對常染色體顯性遺傳性視神經萎縮（ADOA）患者的多劑量遞增研究。此前，該藥物在60微克單次遞增劑量試驗中取得了積極的四周安全性和耐受性結果。 文件稱，該公司目前正在評估ADOA患者的重複給藥方案，以評估其安全性和初步療效，旨在啟動全球註冊試驗以支持新藥申請之前，建立臨床概念驗證。 文件也補充道，正在進行的I期和II期多劑量遞增研究的結果將於2026年和2027年陸續公佈。 該公司股價在周三的交易中上漲了7%。
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