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Penumbra公司称Storm-PE试验表明,血栓切除术联合抗凝治疗可改善功能性结果

-- Penumbra (PEN) 周一宣布,STORM-PE 随机对照试验的 90 天结果显示,接受计算机辅助真空血栓切除术 (CAVT) 联合抗凝治疗的中高危急性肺栓塞患者的功能改善程度优于仅接受抗凝治疗的患者。 在六分钟步行试验中,CAVT 联合抗凝治疗组的患者平均步行距离更长,达到 479 米,而仅接受抗凝治疗组为 368 米;CAVT 联合抗凝治疗组达到预测步行距离的 94%,而仅接受抗凝治疗组为 75.2%。此外,根据纽约心脏协会 (NYHA) 功能分级,CAVT 联合抗凝治疗组报告无身体活动受限的患者比例也更高,达到 97%,而仅接受抗凝治疗组为 76%。 90 天的安全性结果在两组之间相当,均未发生器械相关死亡,7 天后未发生其他肺栓塞相关死亡,且症状复发率无差异。 这些数据已在介入放射学会年会上公布。Penumbra公司表示,关于接受CAVT治疗的患者长期生活质量和功能预后的Strike-PE中期数据将于4月15日在同一会议上公布。

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