-- Medicenna Therapeutics (MDNA.TO) 股价接近 52 周低点，该公司周二在圣地亚哥举行的美国癌症研究协会 (AACR) 年会上以海报形式展示了其主要候选药物 MDNA113 的最新“积极”临床前数据。 声明称，在一项头对头的非人灵长类动物研究中，MDNA113 在高达 50 mg/kg 的剂量下耐受性良好，而对照组由于出现严重毒性（包括血管渗漏综合征），无法在较低剂量下进行第二次给药。 MDNA113 旨在解决该类药物第一代分子在安全性和剂量方面的局限性。Medicenna 首席执行官 Fahar Merchant 表示：“综合来看，这些数据表明，MDNA113 是一种首创的 PD-1 x IL-2 双功能药物，其精妙的设计使其具有更优异的耐受性和更宽的治疗窗口，优于第一代疗法。” 周一，Medicenna股票在多伦多证券交易所收盘下跌0.01美元，至0.60美元，接近52周低点。
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Asia Markets
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