-- Immunome（IMNM）周三宣布，已向美国食品药品监督管理局（FDA）提交了新药申请，申请上市的药物为varegacestat，一种用于治疗成人纤维瘤的在研口服药物。 该公司表示，此次申请基于积极的3期RINGSIDE试验结果，结果显示与安慰剂相比，varegacestat显著改善了患者的无进展生存期，降低了84%的疾病进展或死亡风险，客观缓解率达到56%。 该公司补充说，试验的详细数据将在2026年美国临床肿瘤学会（ASCO）年会上公布。 Immunome股价周三下跌2.7%。
Price: $23.18, Change: $-0.53, Percent Change: -2.24%
Apellis Pharmaceuticals (APLS) has an average rating of hold and mean price target of $40.82, according to analysts polled by FactSet.(covers equity, commodity and economic research from major banks and research firms in North America, Asia and Europe. Research providers may contact us here: https://www..com/contact-us)Price: $40.95, Change: $-0.05, Percent Change: -0.11%
Terns Pharmaceuticals (TERN) has an average rating of hold and mean price target of $53, according to analysts polled by FactSet.
CFRA, an independent research provider, has providedwith the following research alert. Analysts at CFRA have summarized their opinion as follows:We lower our 12-month target price by $8 to $196, 19x our 2026 EPS estimate (unchanged) and a discount to its 23x five-year average forward multiple, reflecting geopolitical risks. We lower our 2026 EPS to $10.33 from $10.74 and 2027's to $11.58 from $12.07, primarily reflecting lower gross bookings growth from the Middle East conflict. We maintain our Buy opinion as shares are undervalued given long-term competitive strengths and temporary geopolitical headwinds. The company's Connected Trip platform and Genius loyalty program are supporting higher-margin direct bookings, suggesting AI initiatives are strengthening consumer engagement rather than disintermediating the platform. Strong free cash flow supports future shareholder returns, including $3.6 billion in Q1 buybacks. While the Middle East conflict will impact Q2 bookings, BKNG has a history of seeing travel rebound following geopolitical or economic disruptions. U.S. room night growth accelerated in Q1 to a low-teens range, providing near-term momentum.