-- GSK（グラクソ・スミスクライン）は月曜日、同社の肝疾患治療薬エフィモスフェルミンが、代謝機能障害関連脂肪性肝炎（MASH）の治療薬として、米国食品医薬品局（FDA）から画期的治療薬指定（Breakthrough Therapy Designation）を、欧州医薬品庁（EMA）から優先医薬品指定（Priority Medicines Designation）を取得したと発表した。 FDAの指定は医薬品の開発・審査を迅速化することを目的としており、EMAの指定は科学的・規制上の支援を提供するものである。 これらの指定は、中等度から進行期の肝線維症および肝硬変患者を対象とした第2相試験データに基づいている。このデータでは、プラセボと比較して肝線維症の改善とMASHの寛解が認められた。同社は、この治療薬は概ね良好な安全性プロファイルを示したと述べている。 同社は、肝線維症を伴うMASH患者を対象とした第3相試験を今年中に開始する予定であると発表した。
Price: $54.48, Change: $+0.04, Percent Change: +0.06%
James C Baker, Director, President, on April 27, 2026, executed a purchase for 25,000 shares in Kayne Anderson Energy Infrastructure Fund (KYN) for $339,250. Following the Form 4 filing with the SEC, Baker has control over a total of 1,003,019 common shares of the company, with 1,003,019 shares held directly.SEC Filing:https://www.sec.gov/Archives/edgar/data/1293613/000133167426000004/xslF345X05/primary_doc.xmlPrice: $13.51, Change: $+0.09, Percent Change: +0.66%
Two Iran-linked tankers are sailing west after US forces boarded them on April 21 and 23, with their destination still unclear, according to a Bloomberg analysis on Monday.US forces boarded the Tifani and the Phonix, also known as Majestic X, during maritime interdiction operations near Sri Lanka, the analysis said, citing the Pentagon.Tracking signals show both vessels traveling west across the Indian Ocean while staying close to each other, the analysis added.US authorities have not outlined the next steps for the ships, keeping their future route and handling unclear, according to the analysis.Despite sailing west, both tankers continue signaling Asian destinations, adding to the uncertainty over their final destinations, the analysis said.Their current path aligns with routes toward Cape Town or toward Diego Garcia in the Chagos archipelago, where the US operates a military base, the analysis noted.The US previously diverted shipments to its own ports after intercepting Venezuelan cargoes in the Caribbean Sea during a similar blockade, according to the analysis.The US began targeting Iran-linked shipping on April 13 after Tehran closed the Strait of Hormuz following attacks that started in late February, the analysis said.Although vessels can alter tracking signals, current data shows no signs of manipulation for either tanker, according to the analysis.The US Central Command did not immediately respond to' request for comments.
Real Brokerage (REAX) said Monday it agreed to acquire RE/MAX (RMAX) in a deal with an enterprise value of approximately $880 million.The agreement values each RE/MAX share at $13.80, giving shareholders the option to receive either $13.80 in cash or 5.15 shares of the newly formed Real REMAX Group, the company said.Real Brokerage's CEO Tamir Poleg will serve as chairman and CEO of the combined entity following the deal's expected closing in H2, the company said.Real Brokerage's shares were down roughly 27% while RE/MAX's stock was up nearly 21% in Monday trading.Price: $1.92, Change: $-0.76, Percent Change: -28.25%