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German Shares Slip; Qiagen Tumbles on Outlook Downgrade

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The German blue-chip DAX was down 0.27% on Tuesday, as investors assess the ongoing diplomatic stalemate between the US and Iran alongside the latest round of corporate earnings and trading updates.

Qiagen (QIA.F) was DAX's worst performer, falling 10.76%, after lowering its full-year 2026 net sales outlook to between 1% and 2% growth at constant exchange rates, down from its earlier target of at least 5%. The molecular testing company also projects a 2% decline in net sales from last year's $534 million.

Concurrently, Bayer's (BAYN.F) shares retreated by 4.01%, after Bloomberg News reported the US Supreme Court signaled a split opinion on how to handle ongoing Roundup lawsuits. Despite the market's reaction, mwb Research characterized the hearing of Monsanto v. Durnell as "broadly neutral to slightly constructive," viewing it as another part of the German life sciences company's broader strategy to contain its Roundup litigation liabilities.

"While oral arguments provided no decisive read through and justices appeared divided, Supreme Court pre-emption remains a credible catalyst alongside the pending USD 7.25bn settlement, both of which improve visibility around Bayer's largest structural overhang. A favorable ruling would not eliminate all litigation immediately, but it would strengthen Bayer's legal position, reducing future cash uncertainty and supporting sentiment around the Crop Science business. With the market still over-discounting prolonged litigation drag, we reiterate our BUY rating and unchanged [price target] of EUR 52.00, as we continue to see scope for multiple re-rating," mwb said.

In economic news, consumer inflation expectations in the euro area rose. Based on the latest monthly European Central Bank Consumer Expectations Survey, median expectations for inflation for the next 12 months and the next three years increased in March to 4% and 3%, respectively, from 2.5% a month ago. Meanwhile, the forecast for the next five years ticked up to 2.4% from 2.3% in February.

"Ahead of Thursday's ECB meeting, this morning's data provides more evidence that the war in the Middle East and the rise in energy prices are not only posing an inflationary shock but rather a stagflationary shock for the eurozone economy. As much as the rise in inflation expectations will fuel the rate hike debate, growing signs of adverse growth effects will make aggressive rate hikes less straightforward. Even though the ECB's primary policy goal is price stability, it's hard to see that it would really want to fight an exogenous supply shock at the cost of worsening an economic downturn," ING wrote.

Speaking of the Middle East conflict, Iran's latest proposal to sideline talks about its nuclear program until the end of hostilities goes against US President Donald Trump's demands, Reuters reported, citing an unnamed US official. Trump is reportedly "unhappy" with the new terms from Tehran, insisting that nuclear issues be addressed from the outset, the news publication added.

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Asia Markets

US Equity Indexes Mixed Ahead of Trump's Response to Iran's New Peace Proposal

US equity indexes were mixed on Monday, while crude oil futures rose with government bond yields, as investors awaited President Donald Trump's response to Iran's new peace proposal offering safe passage through the Strait of Hormuz.The Nasdaq Composite rose 0.2% to 24,887.10, and the S&P 500 edged up 0.1% to 7,173.91, each hitting an intraday record high ahead of big-tech quarterly results due mid-week. The Dow Jones Industrial Average fell 0.1% to 49,167.79.Iran has made a new offer to stop its attacks on ships in Hormuz in exchange for a full end to the war, including the US's lifting of its naval blockade of Iranian ports and the postponement of nuclear negotiations, The Wall Street Journal reported, citing officials familiar with the matter.Iranian Foreign Minister Abbas Araghchi presented the offer during his tour of the region and Pakistan over the weekend. Trump discussed the proposal with his national security team on Monday, White House press secretary Karoline Leavitt said. The president earlier said negotiations with Iran could happen over the phone instead of in person."We doubt that the US will go for this, since the US's economic blockade of Iran remains its key 'pressure tactic' in making Iran concede to the US's fundamental demands pertaining to Iran's power," Thierry Wizman, global foreign-exchange and rates strategist at Macquarie, said in a note.West Texas Intermediate crude oil futures rose 2.2% to $96.48, and Brent crude futures advanced 2.6% to $108.09.In precious metals, gold futures fell 1% to $4,695.1, and silver futures declined 1.4% to $75.36.Most US Treasury yields rose, with the 10-year up three basis points to 4.34%, and the two-year climbed 2.3 basis points to 3.8%.In company news, Shell (SHEL) agreed to acquire Canadian energy company ARC Resources in a cash-and-stock deal with an enterprise value of US$16.4 billion, as the oil and gas giant looks to increase its exposure to low-cost shale gas and liquids production in Canada's Montney basin.Domino's Pizza (DPZ) reported weaker-than-expected Q1 results, with the company's chief executive officer saying consumer uncertainty and inflation weighed on demand late in the quarter. Shares slumped 8.8%, the worst performer on the S&P 500.Sandisk (SNDK) is expected to post another "strong" quarter and full-year outlook, benefiting from pricing momentum for NAND memory systems, Morgan Stanley said in a note Monday. Shares of Sandisk were up 8.1%, the top gainer on the Nasdaq.In economic news, the Dallas Fed's monthly manufacturing index fell to minus 2.3 in April from minus 0.2 in March, compared with expectations for a 0.8 print. The index indicates faster contraction, in contrast with other regional manufacturing readings already released.

Dow JonesNasdaq CompositeS&P 500$DPZ$SHEL$SNDK
Asia Markets

US Equity Indexes Decline, Crude Oil Jump Amid Stalled Iran Peace Talks

US equity indexes declined in Monday's midday trading as deadlocked negotiations to find a lasting solution for the Iran war pushed crude oil futures higher.The Nasdaq Composite fell 0.2% to 24,785.2, with the Dow Jones Industrial Average lower by 0.1% to 49,172.3. The S&P 500 was little changed at 7,167.6. All sectors except communication services, financials, and utilities fell. Consumer staples and materials led the decliners.In the absence of any face-to-face discussions in Pakistan this weekend, Iran offered a proposal to reopen the Strait of Hormuz and end the war, Axios cited a US official and two people with knowledge of the matter in a news report. That proposal, however, includes postponing nuclear negotiations between the two countries, according to the Axios report.President Donald Trump plans to meet with top national security officials today, according to two sources, to discuss the new Iranian proposal that would reopen Hormuz, CNN reported.Iranian Foreign Minister Abbas Araghchi is in Russia ahead of a meeting with President Vladimir Putin, following meetings in Pakistan and Oman. Araghchi gave Pakistani officials a list of "red lines" to be conveyed to the US, including "nuclear issues and the Strait of Hormuz," according to CNN.West Texas Intermediate crude oil futures jumped 3.4% to $97.62, and Brent crude futures advanced 4.2% to $109.75."Oil continues to grind higher as the Strait of Hormuz remains effectively closed, extending disruptions across the Middle East that continue to tighten the availability of critical commodities - from crude, fuel and gas to metals, fertilizers and petrochemicals," Saxo Bank analysts said in a note."Brent crude trades at a three-week high as efforts to revive peace talks have stalled, with an Iranian proposal reportedly calling for nuclear negotiations to be postponed to a later stage," the analysts said.In precious metals, gold futures dropped 1.2% to $4,683.80, and silver futures declined 1.9% to $75.49, as higher crude oil prices raise inflation concerns.Most US Treasury yields rose, with the 10-year up three basis points to 4.34% and the two-year climbed 3.2 basis points to 3.81%.In company news, Shell (SHEL) agreed to acquire Canadian energy company ARC Resources in a cash-and-stock deal with an enterprise value of $16.4 billion, as the oil and gas giant looks to increase its exposure to low-cost shale gas and liquids production in Canada's Montney basin.Domino's Pizza (DPZ) reported weaker-than-expected Q1 results, with the company's chief executive officer saying consumer uncertainty and inflation weighed on demand late in the quarter. Shares slumped 10%, the worst performer on the S&P 500.Sandisk (SNDK) is expected to post another "strong" quarter and full-year outlook, benefiting from pricing momentum for NAND memory systems, Morgan Stanley said in a note Monday. Shares of Sandisk were up 7.5%, the top gainer on the Nasdaq.In economic news, the Dallas Fed's monthly manufacturing index fell to minus 2.3 in April from minus 0.2 in March, compared with expectations for a 0.8 print. The index indicates faster contraction, in contrast with other regional manufacturing readings already released.

Dow JonesNasdaq CompositeS&P 500$DPZ$SHEL$SNDK
Asia Markets

Exchange-Traded Funds Edge Lower as US Equities Fall After Midday

Broad Market IndicatorsBroad-market exchange-traded fund IWM and IVV edged lower. Actively traded Invesco QQQ Trust (QQQ) eased 0.1%.US equity indexes declined in midday trading Monday as deadlocked negotiations to end the Iran war and a resulting move higher in crude oil futures hit investor confidence.EnergyIShares US Energy ETF (IYE) and the State Street Energy Select Sector SPDR (XLE) each shed about 0.3%.TechnologyThe State Street Technology Select Sector SPDR ETF (XLK) was down 0.3%; iShares US Technology ETF (IYW) rose 0.1% and iShares Expanded Tech Sector ETF (IGM) lost about 0.3%.The State Street SPDR S&P Semiconductor (XSD) declined 3.7%, and iShares Semiconductor (SOXX) was down 1.9%.FinancialThe State Street Financial Select Sector SPDR (XLF) added 0.7%. Direxion Daily Financial Bull 3X Shares (FAS) climbed 2%, and its bearish counterpart, Direxion Daily Financial Bear 3X Shares (FAZ), declined 2.1%.CommoditiesCrude oil rose 1.9%, and the United States Oil Fund (USO) gained 1.9%. Natural gas was up 2.7%, and the United States Natural Gas Fund (UNG) added 3.2%.Gold on Comex slipped 1.1%, and the State Street SPDR Gold Shares (GLD) fell 0.9%. Silver declined 1.7%, and iShares Silver Trust (SLV) was down 1.1%.ConsumerThe State Street Consumer Staples Select Sector SPDR (XLP) fell 0.7%. The Vanguard Consumer Staples ETF (VDC) shed 0.7%, and iShares Dow Jones US Consumer Goods (IYK) was 0.5% lower.The State Street Consumer Discretionary Select Sector SPDR (XLY) dipped 0.5%. VanEck Retail ETF (RTH) fell 0.4%, while the State Street SPDR S&P Retail (XRT) eased 0.2%.Health CareThe State Street Health Care Select Sector SPDR (XLV) fell fractionally, iShares US Healthcare (IYH) shed 0.1%, and Vanguard Health Care ETF (VHT) was marginally lower. IShares Biotechnology ETF (IBB) fell 0.1%.IndustrialThe State Street Industrial Select Sector SPDR (XLI) slipped 0.2%. Vanguard Industrials Index Fund (VIS) and iShares US Industrials (IYJ) also dropped.CryptocurrencyIn midday activity, bitcoin (BTC-USD) fell 2.1%. Among cryptocurrency ETFs, ProShares Bitcoin ETF (BITO) dipped 1.4%, ProShares Ether ETF (EETH) lost 1.9%, and ProShares Bitcoin & Ether Market Cap Weight ETF (BETH) was down 1.5%.

Dow Jones^EEM^EXI^FAS^FAZ^GLD^IBB^IGM^IGV^IPK^IVV^IWMNasdaq Composite^IYE^IYH^IYJ^IYK^IYW^PMR^QQQ^RTH^SOXXS&P 500^SPY^UNG^USO^VDC^VHT^VIS^XLE^XLF^XLI^XLK^XLP^XLV^XRT^XSD$BETH$BITO$EETH