-- Entropy Neurodynamics（ASX：ENP）週一向澳洲證券交易所提交的文件顯示，其候選藥物TRP-8802在一項針對腸躁症（IBS）的2a期臨床研究中顯示出75%的有效率。 該公司表示，這一結果標誌著IBS藥物研發領域“迄今為止最強的臨床信號”，與目前有效率在17%至44%之間的療法相比，代表著治療上的突破。 研究分析了12名先前接受過多種標準治療但均告失敗的患者，在接受兩種劑量的TRP-8802口服裸蓋菇素合併結構化心理療法治療後的療效。 Entropy表示，數據顯示，該候選藥物針對的是根本的神經生物學通路，而不僅僅是掩蓋這種慢性疾病的症狀。 文件顯示，TRP-8802的安全性與迷幻劑輔助療法的預期相符，記錄到的唯一一起嚴重不良事件已在臨床支持下解決。 該公司表示，其在合作談判、更大規模的臨床試驗和資助機會方面處於有利地位，並制定了明確的研發路徑，並專注於美國市場。在美國，患者每年在治療疾病上的花費超過600億美元。 Entropy Neurodynamics的股價在周一的交易中上漲了3%。
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