-- Entropy Neurodynamics（ASX：ENP）周一向澳大利亚证券交易所提交的文件显示，其候选药物TRP-8802在一项针对肠易激综合征（IBS）的2a期临床研究中显示出75%的有效率。 该公司表示，这一结果标志着IBS药物研发领域“迄今为止最强的临床信号”，与目前有效率仅为17%至44%的疗法相比，代表着治疗上的突破。 该研究分析了12名此前接受过多种标准治疗但均无效的患者，在接受两种剂量的TRP-8802口服裸盖菇素联合结构化心理疗法治疗后的疗效。Entropy表示，数据显示，该候选药物靶向的是根本的神经生物学通路，而不仅仅是掩盖这种慢性疾病的症状。 文件显示，TRP-8802的安全性与迷幻剂辅助疗法的预期相符，记录到的唯一一起严重不良事件已在临床支持下得到解决。 该公司表示，其在合作谈判、更大规模的临床试验和资助机会方面处于有利地位，并制定了明确的研发路径，重点关注美国市场。在美国，患者每年在治疗该疾病上的花费超过600亿美元。 Entropy Neurodynamics的股价在周一的交易中上涨了3%。
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