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Entrada Therapeutics股價下跌,先前有通報其治療杜氏肌肉營養不良症的藥物未達分析師預期。

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-- 根據路透社週四報導,Entrada Therapeutics (TRDA) 的股價在周四下午的交易中暴跌近 58%,因為該公司用於治療杜氏肌肉營養不良症兒童的藥物在早期至中期臨床試驗中未能達到分析師的預期。 Entrada 週四表示,接受治療的患者肌肉營養不良蛋白水平較基線水平 4% 僅增加了 2.36%。 路透社報道稱,William Blair 分析師 Myles Minter 先前預計,該藥物的安慰劑校正後肌肉營養不良蛋白水平至少會增加 10%,而該公司自身的模型估計約為 11%。 此外,該數據也遜於 Avidity Biosciences 的競爭對手藥物 del-zota(一種外顯子 44 跳躍療法),後者在早期至中期臨床試驗中報告稱,安慰劑校正後的肌肉營養不良蛋白水平增加了約 25%。路透社也指出,Oppenheimer 的分析師先前也曾將此標準作為 Entrada 成功與否的基準。

Price: $6.77, Change: $-9.26, Percent Change: -57.77%

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