-- 吉利德科学公司（GILD）周三宣布，美国食品药品监督管理局（FDA）已受理其每日一次的HIV治疗药物新药申请，该药物为比克替拉韦和来那卡帕韦的复方制剂，并授予优先审评资格，预计审批日期为8月27日。 该公司表示，该申请基于ARTISTRY-1和ARTISTRY-2两项III期临床试验，结果显示该方案在48周内维持了病毒抑制，且在HIV感染成人患者中总体耐受性良好，包括那些从多片复方制剂或Biktarvy转换而来的患者。 该公司还表示，比克替拉韦75毫克和来那卡帕韦50毫克的复方制剂目前仍处于研究阶段，尚未在全球范围内获批，其安全性和有效性尚待进一步证实。
Price: $128.49, Change: $-0.77, Percent Change: -0.60%
Price: $671.00, Change: $-0.35, Percent Change: -0.05%
US equity indexes fell ahead of Wednesday's close as crude oil futures and government bond yields rose amid concern that no end is in sight for the Iran war.The Federal Open Market Committee maintained its target rate at a policy meeting, but beneath that outcome, the level of dissent was, reportedly, the highest since 1992. Fed Chair Jerome Powell said in a press conference after the meeting that he could stay as governor "at least" until the central bank's legal challenges are resolved.Index heavyweights Alphabet (GOOG, GOOGL), Amazon.com (AMZN), Meta Platforms (META), and Microsoft (MSFT) will report quarterly earnings after the bell, adding to frayed nerves as investors await the latest read on the hyperscalers' capital expenditure plans.The Dow Jones Industrial Average fell 0.6% to 48,860.1, with the S&P 500 down 0.1% to 7,129.2. The Nasdaq Composite slipped 0.1% to 24,639.5.President Donald Trump has instructed aides to prepare for an extended blockade of Iran, US officials told The Wall Street Journal. In recent meetings, including a Monday discussion in the Situation Room, Trump opted to continue squeezing Iran's economy and oil exports by preventing shipping to and from its ports, the WSJ reported.West Texas Intermediate crude oil futures jumped 8.2% to $108.15, and Brent crude futures surged 7.8% to $119.97 amid concern that Trump's policy will prolong disruption in the Strait of Hormuz, the chokepoint for 20% of global crude oil flows.The FOMC maintained its target rate at 3.50% to 3.75%, as expected, but four officials dissented, its statement showed late Wednesday.Fed Governor Stephen Miran again sought a 25-basis-point rate. Cleveland Fed President Beth Hammack, Minneapolis Fed President Neel Kashkari, and Dallas Fed President Lorie Logan supported holding rates steady but "did not support inclusion of an easing bias in the statement at this time," according to the statement.Chair Powell said he will continue to serve as a Fed Governor after his term as chair ends next month. Powell's term as governor is due to end in January 2028, but he could leave before the expiry. "I will stay until it is appropriate for me to leave."
Chi Fung Cheng, Director, Chief Technology Officer, on April 27, 2026, sold 27,500 shares in Credo Technology Group Holding (CRDO) for $4,931,442. Following the Form 4 filing with the SEC, Cheng has control over a total of 6,161,156 ordinary shares of the company, with 108,786 shares held directly and 6,052,370 controlled indirectly.SEC Filing:https://www.sec.gov/Archives/edgar/data/1807794/000162828026028331/xslF345X05/wk-form4_1777492236.xmlPrice: $174.84, Change: $+8.92, Percent Change: +5.37%