-- 水曜午後、ヘルスケア関連株は下落し、ニューヨーク証券取引所ヘルスケア指数は0.4%安、ステート・ストリート・ヘルスケア・セレクト・セクターSPDR ETF（XLV）は0.7%安となった。 iシェアーズ・バイオテクノロジーETF（IBB）は1.7%安となった。 企業ニュースでは、バイオ医薬品大手アッヴィ（ABBV）が水曜、通期業績見通しを引き上げた。同社は、免疫治療薬「スカイリジ」と「リンヴォック」の力強い売上成長に牽引され、第1四半期決算が予想を上回った。同社の株価は3.3%上昇した。
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Earnings Flash (META) Meta Platforms Posts Q1 Revenue $56.31B, vs. FactSet Est of $55.56B
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Japan
US Equity Indexes Fall Amid Surge in Crude Oil Prices, Dissent in Fed Policy Highest in Over 3 Decades
US equity indexes fell ahead of Wednesday's close as crude oil futures and government bond yields rose amid concern that no end is in sight for the Iran war.The Federal Open Market Committee maintained its target rate at a policy meeting, but beneath that outcome, the level of dissent was, reportedly, the highest since 1992. Fed Chair Jerome Powell said in a press conference after the meeting that he could stay as governor "at least" until the central bank's legal challenges are resolved.Index heavyweights Alphabet (GOOG, GOOGL), Amazon.com (AMZN), Meta Platforms (META), and Microsoft (MSFT) will report quarterly earnings after the bell, adding to frayed nerves as investors await the latest read on the hyperscalers' capital expenditure plans.The Dow Jones Industrial Average fell 0.6% to 48,860.1, with the S&P 500 down 0.1% to 7,129.2. The Nasdaq Composite slipped 0.1% to 24,639.5.President Donald Trump has instructed aides to prepare for an extended blockade of Iran, US officials told The Wall Street Journal. In recent meetings, including a Monday discussion in the Situation Room, Trump opted to continue squeezing Iran's economy and oil exports by preventing shipping to and from its ports, the WSJ reported.West Texas Intermediate crude oil futures jumped 8.2% to $108.15, and Brent crude futures surged 7.8% to $119.97 amid concern that Trump's policy will prolong disruption in the Strait of Hormuz, the chokepoint for 20% of global crude oil flows.The FOMC maintained its target rate at 3.50% to 3.75%, as expected, but four officials dissented, its statement showed late Wednesday.Fed Governor Stephen Miran again sought a 25-basis-point rate. Cleveland Fed President Beth Hammack, Minneapolis Fed President Neel Kashkari, and Dallas Fed President Lorie Logan supported holding rates steady but "did not support inclusion of an easing bias in the statement at this time," according to the statement.Chair Powell said he will continue to serve as a Fed Governor after his term as chair ends next month. Powell's term as governor is due to end in January 2028, but he could leave before the expiry. "I will stay until it is appropriate for me to leave."
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Insider Trading
Credo Technology Group Holding Insider Sold Shares Worth $4,931,442, According to a Recent SEC Filing
Chi Fung Cheng, Director, Chief Technology Officer, on April 27, 2026, sold 27,500 shares in Credo Technology Group Holding (CRDO) for $4,931,442. Following the Form 4 filing with the SEC, Cheng has control over a total of 6,161,156 ordinary shares of the company, with 108,786 shares held directly and 6,052,370 controlled indirectly.SEC Filing:https://www.sec.gov/Archives/edgar/data/1807794/000162828026028331/xslF345X05/wk-form4_1777492236.xmlPrice: $174.84, Change: $+8.92, Percent Change: +5.37%
$CRDO