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エラスカ社の株価は、第1相用量漸増試験の予備データ発表後に下落した。

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-- エラスカ（ERAS）の株価は火曜日、同社がRAS変異を有する固形腫瘍（大腸がん、非小細胞肺がん、膵腺がんなど）患者を対象とした治験薬ERAS-0015の第1相用量漸増試験の予備データを発表したことを受け、48%下落した。 米国と中国で進行中の治験の予備データによると、ERAS-0015は標準治療用量のパニツムマブと併用可能であり、将来の併用療法における基幹治療薬となる可能性を示唆していると、同社は述べた。 声明によると、この治療法は概ね「忍容性が良好」であり、用量制限毒性や有害事象による治療中止は認められなかった。 エラスカは、今後の研究における推奨用量として1日1回24mgと32mgを選択し、パニツムマブとの併用において「有望な臨床的可能性」を示したと述べた。 同社は規制当局への提出書類の中で、重度の前治療を受けた転移性膵腺癌の66歳の男性患者が死亡したと発表した。同社によると、グレード3の治療関連有害事象である肺炎は、患者の意思による支持療法の中止後、グレード5に進行したという。

Price: $9.96, Change: $-9.20, Percent Change: -48.02%

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