-- アクソム・セラピューティクス（AXSM）は木曜日、アルツハイマー病に伴う興奮状態の治療薬として、米国食品医薬品局（FDA）がオーベリティを承認したと発表した。 今回の承認は、プラセボと比較してオーベリティが興奮症状を著しく改善し、再発までの期間を延長したことを示す2つの第3相臨床試験の結果に基づいている。 同社によると、オーベリティは脳内のN-メチル-D-アスパラギン酸受容体とシグマ-1受容体に作用し、大うつ病性障害の成人患者にも承認されている。 アクソムの株価は木曜日の取引で12%以上上昇した。
Price: $206.45, Change: $+22.50, Percent Change: +12.23%
Toronto-Dominion Bank (TD.TO) after the close Thursday said it issued its seventh sustainable-labelled bonds for 150-million Swiss francs. The bank said its total sustainable bond issuances have now exceeded C$5.2 billion since 2014."TD's first European green bond continues building the strength of our sustainable financing program, helping us support clients pursuing sustainable investment in a new jurisdiction," said Nicole Vadori, head of sustainability at TD.TD shares closed up $3.40 at $146.33 on Toronto Stock Exchange.
CFRA, an independent research provider, has providedwith the following research alert. Analysts at CFRA have summarized their opinion as follows:Amgen delivered solid Q1 2026 results with revenues of $8.6B (+6% Y/Y), $50M above consensus, and non-GAAP EPS of $5.15 (+5% Y/Y), beating expectations by $0.38. The company demonstrated continued execution of its portfolio diversification strategy, with sixteen products achieving double-digit growth and seventeen products annualizing above $1B. We favorably view AMGN's broad-based growth across newer therapeutic franchises, with standout performances from Repatha (+34% Y/Y), TEPEZZA (+29% Y/Y), and TEZSPIRE (+20% Y/Y), offsetting expected declines in legacy products facing biosimilar competition. Management raised 2026 guidance to $37.1B-$38.5B in revenues and EPS of $21.70-$23.10. R&D expenses surged 16% Y/Y to $1.7B, reflecting intensive investments in the MariTide obesity program and multiple Phase 3 studies. We believe AMGN's successful portfolio transformation and strategic focus on high-growth therapeutic areas position it well for sustained long-term growth.